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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: HOA2_AZOSB (A1K6Y4)

Summary

This is the summary of UniProt entry HOA2_AZOSB (A1K6Y4).

Description: 4-hydroxy-2-oxovalerate aldolase 2 {ECO:0000255|HAMAP-Rule:MF_01656}
Source organism: Azoarcus sp. (strain BH72) (NCBI taxonomy ID 418699)
Length: 342 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam HMGL-like 7 266
disorder n/a 12 14
disorder n/a 21 22
low_complexity n/a 213 234
Pfam DmpG_comm 275 337
low_complexity n/a 332 342

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A1K6Y4. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDLRGTRITV HDMTLRDGMH PKRHLMTLEQ MKTIAQGLDQ AGIPLIEVTH
50
51
GDGLGGSSVN YGFPAHTDEE YLGAVIPLMK QAKVSALLLP GIGTVDHLKM
100
101
AHELGVNTIR VATHCTEADV SEQHISYARK LGMDTVGFLM MAHMNSPEGL
150
151
VQQAKLMESY GANCIYVTDS AGHLLPDTVK ARISAVRDAL KPETELGFHG
200
201
HHNLAMGVAN SIAAIEAGAT RIDAAAAGLG AGAGNTPMEV LIAVCDLMGI
250
251
ETGVDVFKIQ DVAEDLVVPI MDFPIRIDRD ALTLGYAGVY GSFLLFAKRA
300
301
EKKYGVPARE ILVEMGRRGM VGGQEDMIED TAITLAKASA AA        
342
 

Show the unformatted sequence.

Checksums:
CRC64:4C507BC65EB5E8DB
MD5:7ef941723ed5682468d6d966da7aac49

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;