!!

Powering down the Pfam website
On October 5th, we will start redirecting the traffic from Pfam (pfam.xfam.org) to InterPro (www.ebi.ac.uk/interpro). The Pfam website will be available at legacy.pfam.xfam.org until January 2023, when it will be decommissioned. You can read more about the sunset period in our blog post.

Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: MUTL_SHEAM (A1SA23)

Summary

This is the summary of UniProt entry MUTL_SHEAM (A1SA23).

Description: DNA mismatch repair protein MutL {ECO:0000255|HAMAP-Rule:MF_00149}
Source organism: Shewanella amazonensis (strain ATCC BAA-1098 / SB2B) (NCBI taxonomy ID 326297)
Length: 650 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
Pfam HATPase_c_3 21 131
low_complexity n/a 103 115
Pfam DNA_mis_repair 212 328
disorder n/a 333 361
disorder n/a 367 447
disorder n/a 472 473
Pfam MutL_C 483 609
low_complexity n/a 544 558

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A1SA23. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAIQVLPPQL ANQIAAGEVV ERPASVIKEL VENSLDAGAT RVDIDIDKGG
50
51
SKLIRIRDNG GGIPKAELAL ALARHATSKV QTLEDLEAIL SFGFRGEALA
100
101
SISSVSRLTL TSRTTEQAEA WQAYAEGSEV AIRVMPAAHP VGTTIEVADL
150
151
FFNTPARRRF LKSDKTEFTH IDEWLKRIAL IRSDVHFSLS HNGKPVRQYR
200
201
CAATDTQYLQ RLAQVAGRAF ADSAIKVDCQ HDGMGLSGYL QSPALSDMVD
250
251
CHYFYVNGRL IRDRLVNHAV RQAFGELGTF EQPAFVLSLT LDPHQVDVNV
300
301
HPAKHEVRFH QARYVHDFIL QVLQSALSQM QDLPLAEELP RAQESPASVR
350
351
EHTAGYAPYT FNRDAATEAA GVLSSLPDTQ RSQRQPEKAA SGQRSSVDAG
400
401
LSQGSSAHRA SQTGLGQSGN AATFETSERH GSGYSGAGQG QRYVRDQLSG
450
451
QQRQAAQYYA ELLHTPEVVS TSGSLQAGLP MPPLLAGRYW VLAQDEHLRL
500
501
LSISDAAKAL VVQEILSKLP TGLVGQPLLM PVAVAADADW TMILAERESL
550
551
LRRLGLELTI RYQQLIIKKV PPYLRDSQLA KLIPEFLEWI KLEVPADEAL
600
601
CHWLAQYVTG FDAAPKVWQR IQSLEATERN KILESARDLP WQTWLDEYKH
650
651
                                                      
650
 

Show the unformatted sequence.

Checksums:
CRC64:D5DC27F2E6438F30
MD5:a0e0f56b2ee41bfe17cbbbfbce04d1d9

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;