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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: HOA1_NOCSJ (A1SH77)

Summary

This is the summary of UniProt entry HOA1_NOCSJ (A1SH77).

Description: 4-hydroxy-2-oxovalerate aldolase 1 {ECO:0000255|HAMAP-Rule:MF_01656}
Source organism: Nocardioides sp. (strain ATCC BAA-499 / JS614) (NCBI taxonomy ID 196162)
Length: 339 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam HMGL-like 5 264
low_complexity n/a 200 214
low_complexity n/a 253 264
Pfam DmpG_comm 273 333

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A1SH77. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MNAHQIFVQD VTLRDGMHAV RHRIGLDDVR RIVAALDAAG VDAIEVAHGD
50
51
GLAGSSVNYG PGSHTDWEWI EAAADVLERA RLTTLLLPGV GTIHELKTAY
100
101
DLGVRSVRVA THCTEADISA QHITAAREIG MDVSGFLMLS HMAPPAELAK
150
151
QALLMESYGA HCVYVTDSGG RLTMNDVRDR VAAYRDVLDP ATEIGIHAHE
200
201
NLSLSVANSV VAVETGAVRV DASLAGHGAG AGNCPIEAFV AVANLSGFEH
250
251
GCDLFALQDA ADDLVRPLQD RPVRVDRETL TLGYAGVYSS FLRHAERAAD
300
301
QYGVDVRELL MECGRRGLVG GQEDMIIDIA LDQVGAVAS            
339
 

Show the unformatted sequence.

Checksums:
CRC64:AFB7631F54364695
MD5:6970789c6a19dbc3aca27c71450ce071

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;