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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: HOA2_NOCSJ (A1SIM3)

Summary

This is the summary of UniProt entry HOA2_NOCSJ (A1SIM3).

Description: 4-hydroxy-2-oxovalerate aldolase 2 {ECO:0000255|HAMAP-Rule:MF_01656}
Source organism: Nocardioides sp. (strain ATCC BAA-499 / JS614) (NCBI taxonomy ID 196162)
Length: 342 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam HMGL-like 7 266
low_complexity n/a 139 159
low_complexity n/a 177 192
low_complexity n/a 202 217
Pfam DmpG_comm 275 337

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A1SIM3. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MNETRTTVFV QDVTLRDGMH AIRHQLAPGE VAQIAAALDV AGVDAIEISH
50
51
GDGLAGSSLN YGPGSHTDWE WIEAAAANIQ RARLTTLLLP GIGTVDELRK
100
101
AHDLGVRSVR VATHCTEADV SAQHIETARD LGMDVAGFLM MSHMAAASEL
150
151
AAQAALMESY GAHCVYVTDS GGRLTMDAVR DRVRAYRDVL DATTEIGIHA
200
201
HENLSLSVAN SVVAVEAGVT RVDASLAGQG AGAGNCPIEA FVAVANILGW
250
251
QHGCDLYQLQ DAAEDLVRPL QDRPVRVDRE TLTLGYAGVY SSFLRHAEKA
300
301
AQTYDLDVRT ILTEVGNRRL VGGQEDMIVD IAMELSEVAA DR        
342
 

Show the unformatted sequence.

Checksums:
CRC64:885CBD5AAC5FED85
MD5:a032e2bbff469afbde59c2d7438617e7

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;