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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: HOA1_MYCVP (A1T2N6)

Summary

This is the summary of UniProt entry HOA1_MYCVP (A1T2N6).

Description: 4-hydroxy-2-oxovalerate aldolase 1 {ECO:0000255|HAMAP-Rule:MF_01656}
Source organism: Mycolicibacterium vanbaalenii (strain DSM 7251 / JCM 13017 / BCRC 16820 / KCTC 9966 / NRRL B-24157 / PYR-1) (Mycobacterium vanbaalenii) (NCBI taxonomy ID 350058)
Length: 338 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam HMGL-like 4 263
low_complexity n/a 71 86
low_complexity n/a 252 263
Pfam DmpG_comm 272 334

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A1T2N6. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MIRDVYLSDV TLRDGMHAVR HQYSIEQVAM IATALDRAGV DSIEVAHGDG
50
51
LAGGTCNYGF GAHTDLEWIE TVATAVKRAR VATLVLPGVG TVRDLRDARR
100
101
AGATVVRVGT HCTEADISAE HITAARELGM DTVGFLMMSH MSSPSALAAQ
150
151
AKLMEGYGAT CVYVVDSGGA MVMRDVAERV DALRQTLLPA TEIGIHAHHN
200
201
LSLGVANSIT AVQHGAHRVD ASLAGMGAGA GNAPLEVFVA AAERLDWTHG
250
251
CDLHALQDAA DDLVRPLQDR PVRVDRETLT LGYAGVYSSF LRHAEAAAAR
300
301
YHIDARTLLE EAGRRGMVGG QEDMLVDIAL DLTGADRS             
338
 

Show the unformatted sequence.

Checksums:
CRC64:C82C30B344584F65
MD5:c8c0b1d18bb0196e8c798758d4cc6fe9

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;