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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: HOA2_MYCVP (A1TDB7)

Summary

This is the summary of UniProt entry HOA2_MYCVP (A1TDB7).

Description: 4-hydroxy-2-oxovalerate aldolase 2 {ECO:0000255|HAMAP-Rule:MF_01656}
Source organism: Mycolicibacterium vanbaalenii (strain DSM 7251 / JCM 13017 / BCRC 16820 / KCTC 9966 / NRRL B-24157 / PYR-1) (Mycobacterium vanbaalenii) (NCBI taxonomy ID 350058)
Length: 337 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam HMGL-like 4 263
low_complexity n/a 71 86
low_complexity n/a 204 216
low_complexity n/a 261 276
Pfam DmpG_comm 272 334

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A1TDB7. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTTTVYVQDV TLRDGMHAIR HRISPRNVAR IAAALDRAGV DAIEVAHGDG
50
51
LAGSSLSYGP GSHTDWEWID AVAGAVTNAT VTTLLLPGIG TVAQLDEAYR
100
101
RGVRSVRVAT HCTEADIAAQ HIAHARELGM DVSGFLMMSH MAQPADLAAQ
150
151
AKLMESFGAQ SVYVTDSGGR LTMHDVRDRV LAYRDVLAPS TQIGIHAHEN
200
201
LSLAVANSVA AVEAGATRVD ASLAGQGAGA GNCPIEPFVA VADLFGWKHG
250
251
CDLFALQDAA DDIVRPLRDR PVRVDRETLT LGFAGVYSSF LRHAEDASAR
300
301
YGVDTRAILV EVGRRGLIGG QEDMIVDIAL SLSAGVP              
337
 

Show the unformatted sequence.

Checksums:
CRC64:5D4366808A4CF8BC
MD5:0f59d1f61ebfd2e60a066bac78fa53a8

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;