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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: HOA1_MYCSK (A1UM80)

Summary

This is the summary of UniProt entry HOA1_MYCSK (A1UM80).

Description: 4-hydroxy-2-oxovalerate aldolase 1 {ECO:0000255|HAMAP-Rule:MF_01656}
Source organism: Mycobacterium sp. (strain KMS) (NCBI taxonomy ID 189918)
Length: 353 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam HMGL-like 13 272
disorder n/a 19 20
disorder n/a 23 28
low_complexity n/a 266 280
Pfam DmpG_comm 281 343
disorder n/a 350 353

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A1UM80. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSTKDIFFNP IWDVRMTDTS LRDGSHHKRH QFTKDEVGAI VAALDTAGVP
50
51
VIEVTHGDGL GGSSFNYGFS KTPEQELIKL AAETAKEAKI AFLMLPGVGT
100
101
KEDIKEAQNN GGSICRIATH CTEADVSIQH FGLARELGLE TVGFLMMSHT
150
151
IPPEKLAQQA RIMADAGCQC VYVVDSAGAL VLEGVRDRVA ALVAELGDDA
200
201
QVGFHGHENL GLGVANSVEA VRAGAKQIDG SCRRFGAGAG NAPVEALIGV
250
251
FDKIGVKTGI DFFDIADAAE EVVAPAMPAE CLLDRNALIM GYSGVYSSFL
300
301
KHAIRQSERY GVPAHQLLHR AGQRKLIGGQ EDQLIDIALE IKREQDSGAT
350
351
AAH                                                   
353
 

Show the unformatted sequence.

Checksums:
CRC64:8409CA80B8459475
MD5:ecbb1dbb74e95617601fc6e724f0593c

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;