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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: HOA_ACISJ (A1W2K3)

Summary

This is the summary of UniProt entry HOA_ACISJ (A1W2K3).

Description: 4-hydroxy-2-oxovalerate aldolase {ECO:0000255|HAMAP-Rule:MF_01656}
Source organism: Acidovorax sp. (strain JS42) (NCBI taxonomy ID 232721)
Length: 342 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam HMGL-like 4 263
disorder n/a 18 19
low_complexity n/a 210 231
Pfam DmpG_comm 272 334

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A1W2K3. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTQKITLHDM TLRDGMHPKR HLMTLEQMKS VAQGLDAAGV PLIEVTHGDG
50
51
LGGASVNYGF PAHSDEEYLG TVIPLMKQAK VSALLLPGIG TVDHLKMAHG
100
101
LGVHTIRVAT HCTEADVSEQ HITMARKLDM DTVGFLMMAH MNDAAGLVKQ
150
151
ARLMEGYGAN CIYVTDSAGY LLPDQVTERI AAVRAALKPE TELGFHCHHN
200
201
LAMGVANSIA AIQAGANRID AAAAGLGAGA GNTPLEVLVA VLDRMGIDTG
250
251
VDVWKIQDVA EDLVVPLMDF PIRIDRDALT LGYAGVYGSF LLFAKRAEKK
300
301
YGIPARDLLV ELGRRGMVGG QEDMIEDTAL TMARARGLTV NA        
342
 

Show the unformatted sequence.

Checksums:
CRC64:C947D821EA34A85D
MD5:64b5b7c82ef5c9825c2a4a1decf2e446

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;