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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: HOA_VEREI (A1WLL2)

Summary

This is the summary of UniProt entry HOA_VEREI (A1WLL2).

Description: 4-hydroxy-2-oxovalerate aldolase {ECO:0000255|HAMAP-Rule:MF_01656}
Source organism: Verminephrobacter eiseniae (strain EF01-2) (NCBI taxonomy ID 391735)
Length: 344 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam HMGL-like 7 266
disorder n/a 21 22
low_complexity n/a 213 234
Pfam DmpG_comm 275 337

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A1WLL2. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTLKGKQITV HDMTLRDGMH PKRHLMTLEQ MKTIACGLDA AGVPLIEVTH
50
51
GDGLGGSSVN YGFPAHSDEQ YLSAVIPLVK QAKVSALLLP GIGTVDHLKM
100
101
AHGLGVHTIR VATHCTEADV SEQHIRFARK LEMDTVGFLM MAHMASPEKL
150
151
LEQAKLMEGY GANCIYVTDS AGHLLPETVK TRVGAVREAL KPETELGFHG
200
201
HHNLAMGVAN SIAAIEAGAN RIDAAAAGLG AGAGNTPMEV LIAVCDLMGI
250
251
ATGVDVFKIQ DVAEDLVVPI MDFPIRIDRD ALTLGYAGVY GSFLLFAKRA
300
301
EQKYGVPARD ILVEMGRRGM VGGQEDMIED TAMTMARERG RLAA      
344
 

Show the unformatted sequence.

Checksums:
CRC64:C20DB778D517FBEE
MD5:3cba3278a26c608bb2f085e0d5a85316

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;