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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: HOA1_METPP (A2SI33)

Summary

This is the summary of UniProt entry HOA1_METPP (A2SI33).

Description: 4-hydroxy-2-oxovalerate aldolase 1 {ECO:0000255|HAMAP-Rule:MF_01656}
Source organism: Methylibium petroleiphilum (strain ATCC BAA-1232 / LMG 22953 / PM1) (NCBI taxonomy ID 420662)
Length: 349 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam HMGL-like 8 267
low_complexity n/a 214 235
Pfam DmpG_comm 276 338
low_complexity n/a 333 349

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A2SI33. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MMNLQGKKIT VHDMTLRDGM HPKRHLMTLD QMKSIASGLD AAGVPLIEVT
50
51
HGDGLGGSSV NYGFPAHSDE EYLGAVIPLM KQAKVSALLL PGIGTVDHLL
100
101
MAKDLGVHTV RVATHCTEAD VSEQHISKAR SLEMDTVGFL MMAHMASPEK
150
151
LVSQALLMEG YGANCIYVTD SAGYMLPDDV TVRLRAVRGA LKPETELGFH
200
201
GHHNLAMGVA NSIAAVDAGA NRIDAAAAGL GAGAGNTPME VFIAVCDRMG
250
251
IATGVDVFRI QDVAEDLVVP IMDHIIRVDR DSLTLGYAGV YSSFLLFAKR
300
301
AEKKYGVPAR EILVELGRRG MVGGQEDMIE DTAMTLARER AAAAHKAAA 
349
 

Show the unformatted sequence.

Checksums:
CRC64:1E386E1625DDC6C6
MD5:d3750d26c80eca41cad1b00e58a761cd

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;