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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: MUTL_METLZ (A2SSN1)

Summary

This is the summary of UniProt entry MUTL_METLZ (A2SSN1).

Description: DNA mismatch repair protein MutL {ECO:0000255|HAMAP-Rule:MF_00149}
Source organism: Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z) (NCBI taxonomy ID 410358)
Length: 588 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam HATPase_c_3 21 135
disorder n/a 122 124
Pfam DNA_mis_repair 213 332
disorder n/a 305 308
disorder n/a 367 392
Pfam MutL_C 401 545
low_complexity n/a 466 478

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A2SSN1. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSRVKILDEE TISHIAAGEV VERAASVVKE LVENAVDADA QIIRIGISAD
50
51
KTGITKISVT DDGIGMDFDD ALLAFRQHAT SKISRPEDLD GITTLGFRGE
100
101
ALASIAAISK VTFTTKERGS PSPEAARVVI HGGELISHSA VGAPEGTSVL
150
151
IDALFYNTPA RRKFQKSVPT ELSHVYDMVE RIALSNRNIS FVLLYNGKER
200
201
FQTFGTGSYP DVIAAVFGST FSKELTPVSG SFGPVKIDGW ITRPGSEMKT
250
251
TQTRFYLSIN GRQVTSRQLQ WAIREGYGTL LPKGMYPAAF LDIVLDPRDV
300
301
DVNVHPTKRE VRLSREREVM RCVQDAVYTS LHEERVFSTA PMPTLARETI
350
351
TTLPVEIVGE PVPVYAGKQE MHEARQAPLK QTEKQLRRTE SADLPETDLF
400
401
VPEVLGQIGD TYILAKNESG DLIVVDQHAA HERIMYDQLL ARSSSAEAGQ
450
451
ELIVPQPITL SKKETAALPD LLDVLAAAGY LLEPFGKDVW MVRSVPVVSS
500
501
TLGDPDTIHA ILDAALDGVG NTDEVLDRVL KTAACRAVVK GNTPLTIEQM
550
551
QRLLRQLMAT KSPYTCPHGR PTTIVLSKSR LAGMFLRT             
588
 

Show the unformatted sequence.

Checksums:
CRC64:9EE01DE79CAC0CF1
MD5:6fa0be418c0dac803b24452f3d6fe312

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;