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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: MUTL_STRSV (A3CR14)

Summary

This is the summary of UniProt entry MUTL_STRSV (A3CR14).

Description: DNA mismatch repair protein MutL {ECO:0000255|HAMAP-Rule:MF_00149}
Source organism: Streptococcus sanguinis (strain SK36) (NCBI taxonomy ID 388919)
Length: 647 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
Pfam HATPase_c_3 21 128
disorder n/a 56 59
disorder n/a 66 69
disorder n/a 122 123
disorder n/a 125 126
disorder n/a 128 129
disorder n/a 135 138
Pfam DNA_mis_repair 209 327
disorder n/a 342 345
disorder n/a 347 352
disorder n/a 357 359
disorder n/a 383 407
disorder n/a 410 412
disorder n/a 419 421
disorder n/a 427 432
Pfam MutL_C 445 591

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A3CR14. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSKIIELPEI LANQIAAGEV IERPSSVVKE LVENSIDAGA SQITIEIEEA
50
51
GLKSIQVTDN GEGIDHEDVP LALRRHATSK IKKQADLFRI RTLGFRGEAI
100
101
PSIASVSRFT IETATEAGRH GTLLVAQGGE IEEHVPTSSP VGTKIKIEDL
150
151
FFNTPARLKY MKSQQAELSH IVDVINRLSL AHPEVAFTLI SDGREMTRTA
200
201
GSGNLRQAIA GIYGLATAKK MVEISASDLD FEVSGYVSLP ELTRANRNYI
250
251
TILINGRYIK NFLLNRAILD GYGSKLMVGR FPLAVINIQI DPYLADVNVH
300
301
PTKQEVRISK ERELMALISQ AIATSLKEQD LIPDALENLA KSTVKRASKP
350
351
EQTSLPLKEN RLYYDKKQND FFLKPQVAEQ QLSFEESAKP VHEATDEKAE
400
401
PQSTSVKFAE RKPVSYDQLD HPELDQASLE RAVDKLEQEE KSSFPELEYF
450
451
GQMHGTYLFA QGKGGLYIID QHAAQERVKY EYYREKIGDV DNSQQQLLVP
500
501
YIFEFPADDM LRIKQRMELL EDAGIFLEEY GANQFILREH PIWFKEEEIE
550
551
AGIYEMCDML LLTKEVSIKK YRAELAIMMS CKRSIKANHS LDDYSARDLL
600
601
FQLSQCDNPY NCPHGRPVLV NFTKSDMEKM FRRIQENHTS LRELGKY   
647
 

Show the unformatted sequence.

Checksums:
CRC64:F1C220DE2AD20829
MD5:5d5d29f599e1a694bfc56d0ba1251a89

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;