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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: MNMA_STRSV (A3CRB2)

Summary

This is the summary of UniProt entry MNMA_STRSV (A3CRB2).

Description: tRNA-specific 2-thiouridylase MnmA {ECO:0000255|HAMAP-Rule:MF_00144}
Source organism: Streptococcus sanguinis (strain SK36) (NCBI taxonomy ID 388919)
Length: 373 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam tRNA_Me_trans 7 204
low_complexity n/a 9 21
disorder n/a 141 142
Pfam tRNA_Me_trans_M 208 276
disorder n/a 222 226
low_complexity n/a 241 255
Pfam tRNA_Me_trans_C 285 360

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A3CRB2. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSDNSKIRVV VGMSGGVDSS VTALLLKEQG YDVIGIFMKN WDDTDEFGVC
50
51
TATEDYKDVA AVADQIGIPY YSVNFEKEYW DRVFEYFLAE YRAGRTPNPD
100
101
VMCNKEIKFK AFLDYALTLG ADYVATGHYA QVKRDQDGLV HMLRGKDNNK
150
151
DQTYFLSQLS QEQLQKTMFP LGHLEKPEVR AIAERAGLAT AKKKDSTGIC
200
201
FIGEKNFKEF LSQYLPAQPG RMMTLEGRDM GQHAGLMYYT IGQRGGLGIG
250
251
GQHGGDNEPW FVVGKDLSQN ILYVGQGFYH DNLMSTSLDA SQVHFTKEMP
300
301
EEFTMECTAK FRYRQPDSKV TVTVKGDKAV VNFDKPQRAI TPGQGVVFYD
350
351
GDECLGGGLI DRAYKNGQVL QYI                             
373
 

Show the unformatted sequence.

Checksums:
CRC64:666FA8AC99A322FF
MD5:fa96155aa8c682523a78a41e55bdc36b

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;