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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: MUTL_SHELP (A3QAD8)

Summary

This is the summary of UniProt entry MUTL_SHELP (A3QAD8).

Description: DNA mismatch repair protein MutL {ECO:0000255|HAMAP-Rule:MF_00149}
Source organism: Shewanella loihica (strain ATCC BAA-1088 / PV-4) (NCBI taxonomy ID 323850)
Length: 631 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam HATPase_c_3 21 136
low_complexity n/a 76 91
low_complexity n/a 101 114
Pfam DNA_mis_repair 212 329
disorder n/a 301 304
disorder n/a 339 341
disorder n/a 347 427
low_complexity n/a 408 422
disorder n/a 433 458
Pfam MutL_C 461 588
low_complexity n/a 475 486

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A3QAD8. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTIRILPPQL ANQIAAGEVV ERPASVIKEL VENSLDAGAT RVDIEIDKGG
50
51
SKLIKITDNG SGIPKEELSL ALSRHATSKL ASLDDLDAIL SFGFRGEALA
100
101
SISSVSRLTL TSRTQEQSEA WQAYAEGSEM AVRVIPAAHP VGSTVEAADL
150
151
FFNTPARRRF LKSDKTEFTH IDEWLKRIAL VRSEIHFTLK HNGKQVRNYR
200
201
PAKTEAQYLQ RLAQVSGKAF ADNALRVDCN HNGLSLSGYI QSPFSEMAVG
250
251
DTQYFYVNGR LVRDRLVNHA VRQAFAQQLQ GEQVAFVLML NLDPHQVDVN
300
301
VHPAKHEVRF HESRYVHDFI LQALESALRQ SSELAFEAAL DTQVTDQNRS
350
351
ASYIRPLQTQ QSDTGSNQIA HGDTEENALW LANERPAYGE REASRQAGGQ
400
401
RVQETQMSSY GSGQSGGRGR SYASTELPSQ AAVDSYAQLM TTPGVSSQAN
450
451
QADDSHLPPM PQVLDGQYWL LVRGSELALL SLSCAAREVT RREIEAKLDA
500
501
GLIGQPLLMP VSVKVDEDWQ QTLVERELLV RKLGLELTIR LGQLIIKKVP
550
551
PYLRQSQLAS VIPEFLQWIR FEEPTTEALV NWLVNQSGEQ FNSASRLWAG
600
601
LMGLPESQQQ EILSLAKVMP WQTWLGEQTS E                    
631
 

Show the unformatted sequence.

Checksums:
CRC64:C42F28DAB9F30ADA
MD5:3aa4cf4545d95f0b0d66883024c40a4d

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;