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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: A5WVZ0_DANRE (A5WVZ0)

Summary

This is the summary of UniProt entry A5WVZ0_DANRE (A5WVZ0).

Description: Ceramide kinase {ECO:0000313|Ensembl:ENSDARP00000117613}
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 649 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 72 77
disorder n/a 145 160
Pfam DAGK_cat 253 370
disorder n/a 307 311
disorder n/a 313 315
Pfam CERK_C 382 640
low_complexity n/a 443 455
disorder n/a 647 649

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A5WVZ0. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEKQSTLLCS ELSVQRRLYE VTLNCAILAW KDVQNAKKHT GRAIYGAVKA
50
51
GSHCVPVCEI IAVQEKEDDS PCKDTGKWQK VPQSPTDSCQ HAFTVYYVER
100
101
TRQHCWRCSN VTFQYSEHSL CLLWIQTIKE QLALLSAQST EELAGVHQPL
150
151
RRKTTRQADL RPQSGPHLFP GFHFHRRDWP HSFSAHPSEL RFYIIADGKE
200
201
PVMKCTGDCF SPRVQLHHLM QLIDGLHQAS RKMQFNCQMN IMMFLPPLYH
250
251
QPGNNGFSLF VSIVTEHANH ARDHLKAEAD LKKYDGVVCV GGDGMFSEIM
300
301
HGLVSRTQQD AGVDENSTEE TLIPCGLRIG IIPAGSTDCI CYATVGSNDP
350
351
VTSALHMVVG DSQPMDVCSV HSDDRFLRYS VSLLGYGFYG DVLKDSERKR
400
401
WMGPARYNIS GVKTFLSHRY YEGTVSFLPA EENLGTPRDK VQCRSGCSIC
450
451
RRSSSDKLLS KEDEASVSDV DCRDTWTVIR GKFLAINAAN MSCACPRSPK
500
501
GLSPSAHLAD GTTDLILVRK CSRVDFLRHL LRHTNKKDQF DHSFVEVYRV
550
551
KQFRFTPRFQ ECGSEMDLRE SRAGGKHFFC QICRENRACG CMSSQSNWNC
600
601
DGEILPHTAI QVRVHCQLIK LFARGIEEQP VFEDLYAHCQ LNNPPNHEP 
649
 

Show the unformatted sequence.

Checksums:
CRC64:2787419A202A19FE
MD5:0f0ee47c689805e7576bb1a6da944f4e

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;