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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: HOA_KLEP7 (A6TAC4)

Summary

This is the summary of UniProt entry HOA_KLEP7 (A6TAC4).

Description: 4-hydroxy-2-oxovalerate aldolase {ECO:0000255|HAMAP-Rule:MF_01656}
Source organism: Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578) (NCBI taxonomy ID 272620)
Length: 338 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam HMGL-like 5 264
low_complexity n/a 63 83
Pfam DmpG_comm 273 335

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A6TAC4. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MNGKKLYISD VTLRDGMHAI RHQYSLAQVQ QIAGALDKAG VDSIEVAHGD
50
51
GLQGSSFNYG FGAHSDIAWI EAAAAAVSQA KIATLLLPGI GTLHDLKAAY
100
101
QAGARVVRVA THCSEADVAA QHIAFARELG MDTVGFLMMS HMISPQALAQ
150
151
QALKMESYGA TCIYVVDSGG AMNMNDIRDR FRALKAVLKP ETATGMHAHH
200
201
NLSLGVANSI VAVEEGCDRI DASLAGMGAG AGNAPLEVFI AAADKLGWQH
250
251
GTDLYALMNA ADELVRPLQD RPVRVDRETL ALGYAGVYSS FLRHSEAAAK
300
301
RYGLSAVDIL VELGKRRMVG GQEDMIVDVA LDLLNRNK             
338
 

Show the unformatted sequence.

Checksums:
CRC64:FEB2817892AB3A03
MD5:29e2f3793cc6d7f16043e9820c402c23

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;