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3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: GCHK_ANADF (A7HD43)

Summary

This is the summary of UniProt entry GCHK_ANADF (A7HD43).

Description: Globin-coupled histidine kinase {ECO:0000303|PubMed:21852234}
Source organism: Anaeromyxobacter sp. (strain Fw109-5) (NCBI taxonomy ID 404589)
Length: 382 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam Protoglobin 6 163
disorder n/a 209 211
low_complexity n/a 247 254
Pfam HATPase_c 278 382
disorder n/a 319 322
disorder n/a 330 334
disorder n/a 363 368

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A7HD43. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTGVPETVFE ELKRYVGWGD GDERALRSLH GAAAPHFPRL AEEFYDRILG
50
51
HEGARTALVG GESQVGHLKV TMIAWLDELL GGPWDEAYWD RRYRIGRVHV
100
101
RIGLPQHYMF GAMNVHRTGL ARLAYERFHG DPPELERVRN ALGKVLDLEL
150
151
AVMLHTYRED LLAQQARVER LSTFGQLVGS IGHDLRNPLG VIETSLYILR
200
201
TRTGEDERAR KHLDRIGEQL GVANGIITNL LDMIRDRPLA REPVELAAVV
250
251
GGAAESVRRP TGVSLALEGL DALPPVEGDP GQLRQVFVNL LENAVFAASP
300
301
EGVVAVRASR ADGLVALDVE DSGPGVDPAT RRRLFEPLIT TKDKGIGLGL
350
351
ALVKRIAERH GGTVEYSDRP GGGARFTVRL PA                   
382
 

Show the unformatted sequence.

Checksums:
CRC64:D007A082ABD1F8EA
MD5:da33b5fa64a4c25bbb1cd34755cd4396

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Protoglobin 6 - 158 5OHF F 6 - 158 Show 3D Structure View in InterPro
6OTD A 6 - 158 Show 3D Structure View in InterPro
6 - 160 5OHE F 6 - 160 Show 3D Structure View in InterPro
7 - 158 5OHE A 7 - 158 Show 3D Structure View in InterPro
B 7 - 158 Show 3D Structure View in InterPro
D 7 - 158 Show 3D Structure View in InterPro
E 7 - 158 Show 3D Structure View in InterPro
G 7 - 158 Show 3D Structure View in InterPro
H 7 - 158 Show 3D Structure View in InterPro
5OHF A 7 - 158 Show 3D Structure View in InterPro
B 7 - 158 Show 3D Structure View in InterPro
D 7 - 158 Show 3D Structure View in InterPro
E 7 - 158 Show 3D Structure View in InterPro
G 7 - 158 Show 3D Structure View in InterPro
H 7 - 158 Show 3D Structure View in InterPro
8 - 158 5OHE C 8 - 158 Show 3D Structure View in InterPro
5OHF C 8 - 158 Show 3D Structure View in InterPro
×

The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;