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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: HOA2_FRASN (A8LEP8)

Summary

This is the summary of UniProt entry HOA2_FRASN (A8LEP8).

Description: 4-hydroxy-2-oxovalerate aldolase 2 {ECO:0000255|HAMAP-Rule:MF_01656}
Source organism: Frankia sp. (strain EAN1pec) (NCBI taxonomy ID 298653)
Length: 336 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam HMGL-like 5 264
low_complexity n/a 244 257
low_complexity n/a 249 264
Pfam DmpG_comm 273 335

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A8LEP8. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSGPNIYLQD VTLRDGMHAI RHRVDPERVG AIVAALDKAG VRAIEVTHGD
50
51
GLAGSSLTYG PGSHTNWEWI EAAVTNASQA TITTLLLPGV GTIAELRRAH
100
101
AMGVGSVRVA THCTEADVAA QHIAAARELG MDVSGFLMMS HMAEPAELAA
150
151
QAKLMESYGA HCVYVTDSGG RLTTDRVRER VRAYRDVLRP DTQIGIHAHE
200
201
NLSLSVANSF AAVEEGAYRV DASLAGQGAG AGNCPIEPFV AVALLLGWDL
250
251
DCDLLALEDA AEDLVRPLQD RPVRVDRETL TLGFAGVYSS FLRHAEIAAE
300
301
TYGVDARSIL IEAGRRKLVG GQEDMLVDIA LAIQPK               
336
 

Show the unformatted sequence.

Checksums:
CRC64:E3FF003476A3D38C
MD5:295164c15a04781ceb09fc41deb53108

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;