!!

Powering down the Pfam website
On October 5th, we will start redirecting the traffic from Pfam (pfam.xfam.org) to InterPro (www.ebi.ac.uk/interpro). The Pfam website will be available at legacy.pfam.xfam.org until January 2023, when it will be decommissioned. You can read more about the sunset period in our blog post.

Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: LAMP5_DANRE (A8WFR0)

Summary

This is the summary of UniProt entry LAMP5_DANRE (A8WFR0).

Description: Lysosome-associated membrane glycoprotein 5
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 275 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
sig_p n/a 1 18
Pfam Lamp 32 207
low_complexity n/a 229 246
transmembrane n/a 230 251

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A8WFR0. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEFQLLLLCS VWALGVCAEQ EVENLSGLST NPERDIFVVR ENGTTCLMAE
50
51
FAVRFLIPYD VLALNGIDLI TEQTSVAIPR GAQIAGKCGP SESELQISWA
100
101
AQAFNFHIYF SKEKRVQGSD GKAPEAEVWK INRVQLVYDT SENTHFINAY
150
151
NPGKHTASTH RLSALVTPAG RSYVCAAQQT LTLISSDHQK GVTVSIYDIQ
200
201
IQPFDINADF VFSEPYKCVT DQREQLEQTL PLVLGLILGL IIVITISVYH
250
251
FHLKLNAAHT QQPTLPRDRS LYKNM                           
275
 

Show the unformatted sequence.

Checksums:
CRC64:20452432C6B9A8C5
MD5:0e18338c032569d1759576f1b2b93163

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;