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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: HOA_CHLAA (A9W9U3)

Summary

This is the summary of UniProt entry HOA_CHLAA (A9W9U3).

Description: 4-hydroxy-2-oxovalerate aldolase {ECO:0000255|HAMAP-Rule:MF_01656}
Source organism: Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) (NCBI taxonomy ID 324602)
Length: 343 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 19
Pfam HMGL-like 3 260
disorder n/a 21 22
low_complexity n/a 218 237
Pfam DmpG_comm 269 331
disorder n/a 336 343

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A9W9U3. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKPPRLTDTT LRDGSHPMRH QFTRQQVATI VQALDRAGVP VIEVSHGDGL
50
51
AGSSLQYGFS HTSEFDLIET ARQHAERAKI AALMLPGIGT RQELKEAVAR
100
101
GVQVVRIATQ CTEADISEQH FGLAKELGLE TVGFLMMAHM RPPEELARQA
150
151
KLMESYGADC VYIVDSAGAM LPQDAAARVQ ALKDTLSVQV GFHAHNNLGL
200
201
GIANTLAALE AGADQIDGCL RGLGAGAGNA ATELLAAVLD RLGLNPGLDV
250
251
FSLMDAAEYV VAPIMPFQPF PDRDAITIGY AGVYSTFLLH AKRAGAQYNV
300
301
DPREILVELG RRQAVAGQED WIIDVALELS RRHQSSARKE SRP       
343
 

Show the unformatted sequence.

Checksums:
CRC64:5849B21D00E46BCF
MD5:00aa8f3e15c7abee6dca98b7f6ad5c21

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;