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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: HOA2_MYCMM (B2HI25)

Summary

This is the summary of UniProt entry HOA2_MYCMM (B2HI25).

Description: 4-hydroxy-2-oxovalerate aldolase 2 {ECO:0000255|HAMAP-Rule:MF_01656}
Source organism: Mycobacterium marinum (strain ATCC BAA-535 / M) (NCBI taxonomy ID 216594)
Length: 347 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam HMGL-like 6 265
disorder n/a 20 21
low_complexity n/a 253 262
Pfam DmpG_comm 274 336
disorder n/a 343 347

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession B2HI25. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTGIWDVRIT DTSLRDGSHH KRHQFIKEEV GAIVAALDAA GVPVIEVTHG
50
51
DGLGGSSFNY GFSKTPEQEL IKLAAQTAKE AKIAFLMLPG VGTKEDIKEA
100
101
QDNGGSICRI ATHCTEADVS IQHFGLAREL GLETVGFLMM AHTIAPEKLA
150
151
AQARIMADAG CQCVYVVDSA GALVLDGVAD RVAALVAELG EDAQVGFHGH
200
201
ENLGLGVANS VEAVRAGAKQ IDGSVRRFGA GAGNAPVEAL IGVFDKIGVK
250
251
TGIDFFDIAD AAEDVVRPAM PAECLLDRNA LIMGYSGVYS SFLKHAVRQS
300
301
ERYGVPAHQL LHRAGQRKLI GGQEDQLIDI ALEIKREQES GQVASRR   
347
 

Show the unformatted sequence.

Checksums:
CRC64:14800877498A58C2
MD5:58ebb3aa1cce24c6f443b35a094bb1b7

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;