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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: HOA1_PARP8 (B2JLM6)

Summary

This is the summary of UniProt entry HOA1_PARP8 (B2JLM6).

Description: 4-hydroxy-2-oxovalerate aldolase 1 {ECO:0000255|HAMAP-Rule:MF_01656}
Source organism: Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 / STM815) (Burkholderia phymatum) (NCBI taxonomy ID 391038)
Length: 349 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam HMGL-like 4 263
low_complexity n/a 26 41
disorder n/a 182 183
disorder n/a 187 189
Pfam DmpG_comm 272 334

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession B2JLM6. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDKKLYISDV TLRDGSHAIR HQYSVAQARR IAIALDDARV DSIEVAHGDG
50
51
LQGGSFNYGF GAHTDIEWIK AVASVVKHAK IATLLLPGIG TVRDLRAAYD
100
101
AGARIARVAT HCTEADISRQ HIEYAREIGM EAVGFLMMSH MQTPRALAEQ
150
151
AKLMESYGAT CCYVVDSGGA MNMNDIRDRM RAFKDTLRPE TQTGIHAHHN
200
201
LSLGIANSIV AVEEGCDRVD ASLAGMGAGA GNAPLEVFIA AAARLGWNHG
250
251
TDLYRLMDAA DDIVRPLQDR PVRVDRETLA LGYAGVYSSF LRHAERAASK
300
301
YGLKTVDILV ELGRRRMVGG QEDMIVDVAL DLCGAREFAS SASGRADLI 
349
 

Show the unformatted sequence.

Checksums:
CRC64:1F72A4A2670C30C9
MD5:757e4be1722c02437c4558e5e63e5545

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;