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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: HOA2_PARP8 (B2JQW0)

Summary

This is the summary of UniProt entry HOA2_PARP8 (B2JQW0).

Description: 4-hydroxy-2-oxovalerate aldolase 2 {ECO:0000255|HAMAP-Rule:MF_01656}
Source organism: Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 / STM815) (Burkholderia phymatum) (NCBI taxonomy ID 391038)
Length: 339 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam HMGL-like 4 263
Pfam DmpG_comm 272 334

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession B2JQW0. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDKKLYISDV TLRDGMHAIR HQYSIQNVQD IARALDEAKV DSIEVAHGDG
50
51
LQGSSFNYGF GAHSDLEWIE AVADVVRHAK IATLLLPGIG TIHDLKAAYD
100
101
AGARVVRVAT HCTEADISKQ HIEYARSLGM DTVGFLMMSH MTTPENLAVE
150
151
AKKMESYGAT CVYVVDSGGA MNMNDIRARF MALKATLDPA TQTGMHAHHN
200
201
LSLGVANSIV AVEEGCDRVD ASLAGMGAGA GNAPLEVFIA AVERMGWHHG
250
251
TDLYRLLDAA DDIVRPLQDR PVRVDRETLA LGYAGVYSSF LRHSEIAANK
300
301
YGLKAVDILV ELGKRRMVGG QEDMIVDVAL DLKKREAHA            
339
 

Show the unformatted sequence.

Checksums:
CRC64:3897287A46C86A9C
MD5:5b8fa69c1e83008b829e9d06501135ed

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;