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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: HOA_METSB (B8ESV2)

Summary

This is the summary of UniProt entry HOA_METSB (B8ESV2).

Description: 4-hydroxy-2-oxovalerate aldolase {ECO:0000255|HAMAP-Rule:MF_01656}
Source organism: Methylocella silvestris (strain DSM 15510 / CIP 108128 / LMG 27833 / NCIMB 13906 / BL2) (NCBI taxonomy ID 395965)
Length: 346 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam HMGL-like 8 267
low_complexity n/a 256 267
Pfam DmpG_comm 276 338

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession B8ESV2. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MARINPNKLY VQDVTLRDGM HSVRHQYSLD AVRAIARALD RAHVDAIEIS
50
51
HGDGITGSTF NYGFGAHDDT EWIAAVAGEC KFSRITVLLL PGIGTVHDLK
100
101
YACEAGARSV RVATHCTEAD VSRQHIEAGR KLGMDTVGFL MMAHMAPVEK
150
151
LVEQALLMES YGAECVYVTD SAGALLPKQY AERVKAVRGA LKPETEIGVH
200
201
THHNLTLGVA NAVAGIEAGA VRVDASLAGM GAGAGNAPLE ALIAVLDRMG
250
251
IETGCDLHML MDAADDLVRP LQDRPVRVDR ESLSLGYAGV YSSFLRHAES
300
301
ASKLYGVDTR DILTELGKRR MVGGQEDMIV DVALDILKSH GAEAAQ    
346
 

Show the unformatted sequence.

Checksums:
CRC64:F1002FB934EF9D37
MD5:98ac5b370c625b2bdf7d33e71ab0235e

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;