!!

Powering down the Pfam website
On October 5th, we will start redirecting the traffic from Pfam (pfam.xfam.org) to InterPro (www.ebi.ac.uk/interpro). The Pfam website will be available at legacy.pfam.xfam.org until January 2023, when it will be decommissioned. You can read more about the sunset period in our blog post.

Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: C0P187_AJECG (C0P187)

Summary

This is the summary of UniProt entry C0P187_AJECG (C0P187).

Description: Xanthine dehydrogenase {ECO:0000313|EMBL:EEH02602.1}
Source organism: Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432) (Darling's disease fungus) (Histoplasma capsulatum) (NCBI taxonomy ID 447093)
Length: 1434 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
Pfam Fer2 34 104
low_complexity n/a 61 75
Pfam Fer2_2 114 196
disorder n/a 126 127
disorder n/a 169 170
disorder n/a 209 222
disorder n/a 224 225
disorder n/a 227 233
low_complexity n/a 240 253
disorder n/a 253 289
low_complexity n/a 260 273
disorder n/a 294 298
Pfam FAD_binding_5 325 511
disorder n/a 519 521
Pfam CO_deh_flav_C 520 624
disorder n/a 648 649
disorder n/a 652 653
disorder n/a 655 659
Pfam Ald_Xan_dh_C 675 783
disorder n/a 678 680
low_complexity n/a 767 778
Pfam MoCoBD_1 793 1040
disorder n/a 855 860
disorder n/a 919 926
Pfam MoCoBD_2 1065 1338

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession C0P187. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MGLPVSNSEV DSIPANAALH AIIKSTYTSS VLQFYLNGRR VELQNPNPHW
50
51
TLLDFIRSQR GLKGTKLGCG EGGCGACTVV LQVRDRSNSR RIKHLSVNAC
100
101
LYPLVGVVGK HVITVEGLGS VDKPHPLQER MGKLHGSQCG FCTPGIVMSL
150
151
YSIIRNAYDP ETGKFSLSDN DIEMKGHLDG NLCRCTGYKP ILQAAKTFIV
200
201
EDLKGQLDEE KNSIPVDANT ESENEAAMYL QGQFTNVHKS STGSCGRSGG
250
251
CCRDKINNES RPSDSSTSTG STSADEHSSQ TSLSEEITLQ PSKKVPQVEL
300
301
AEYSPSSELI YPPSLSKFVD NPVCYGDKEK IWLRPTNLQQ LVDIMAAFPS
350
351
ATIVSGASEI QVEIRFKGSE FAVSVFVSDI EELNKISVPA DLSTSSELVI
400
401
GGNAPLTDIE HVCYGLSSKL GRRGSVFGAM AKVLRYFAGR QIRNVASLAG
450
451
NIATASPISD MNPVLLAINA TVVSRTAEKE HLIPMVTMFR GYRKTALPQG
500
501
GIITQIRIPI PPADAREVTK SYKQAKRKDD DIAIVTAGFR VRFDEQDIVK
550
551
DVSLAYGGMA PITVLATQTI KYLMGKKWSA PETLDGALET LAEEFPLAYD
600
601
VPGSMATYRR TLALSLFVRF WNEVIAHFEL GEVDQSLVEE IHRKISTGTR
650
651
DNYNPHEQRI VGKQIPHLSG LKHATGEAEY VDDMPHQDNE LYGALVLSER
700
701
AHAKIVSVDW TPALAPGLAV GYVDKHSIDP EMNFWGSIVK DEPFFALDEV
750
751
HSHGQPIGMV YAETSLKAQA AARAVKVVYE DLPAILTIDE AIEAKSFFKH
800
801
GKELRKGAPP EKMAEVFAKC DRIFEGTIRC GGQEHFYLET NAALVIPHSE
850
851
DGTMDVWSST QNTMETQEFV SRVIGVPSNR INARVKRMGG AFGGKESRSV
900
901
QLAVILAVAA KKERRPMRAM LNRDEDMMTT GQRNPIMCRW KIGVMNDGKL
950
951
VAIDADCYAN AGFSLDMSGA VMDRCCTHLD NCYYFPNAHI RAWVCKTNTV
1000
1001
TNTAFRGFGG PQAMFIAESF MYAIAEGLNI PIDELRWKNL YEQGQRTPFH
1050
1051
QLIDEDWHIP MLLEQVRKEA KYDERKAQIA KYNAQNKWKK RGICLVPTKF
1100
1101
GLSFATAIHL NQAGASVKIY ADGSILLSHG GTEMGQGLYT KMCQVAAQEL
1150
1151
NAPLESIYTQ DTATYQIANA SPTAASSGSD LNGMAVKNAC DQLNERLKPY
1200
1201
WEKFGRDAPL SKIAHAAYRD RVNLVATGYW KMPKIGHVWG DYNPETVKPM
1250
1251
YYYFTQGVAC TEVELDVLTG DHTVLRTDIK MDVGRSINPA IDYGQVEGAF
1300
1301
VQGQGLFTIE ESLWHSKTGQ LATRGPGTYK IPGFSDIPQE FNVSFLQGVS
1350
1351
WKHLRSIQSS KGVGEPPLFL GATVLFALRD ALLSAREDNG VKEKLILDSP
1400
1401
ATAERLRLAV GDRLVKMGNV AKGEGQKSFF VAIS                 
1434
 

Show the unformatted sequence.

Checksums:
CRC64:C3F41605FF9FC57D
MD5:204abebbef1e1d858d28b864fda0faf9

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;