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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: D3ZZT6_RAT (D3ZZT6)

Summary

This is the summary of UniProt entry D3ZZT6_RAT (D3ZZT6).

Description: tRNA-splicing endonuclease subunit 54 {ECO:0000313|Ensembl:ENSRNOP00000006327}
Source organism: Rattus norvegicus (Rat) (NCBI taxonomy ID 10116)
Length: 525 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 15
low_complexity n/a 2 14
low_complexity n/a 16 30
disorder n/a 28 32
disorder n/a 34 46
Pfam tRNA_int_end_N2 63 130
low_complexity n/a 196 208
disorder n/a 203 204
disorder n/a 217 328
low_complexity n/a 313 323
disorder n/a 332 335
disorder n/a 337 365
coiled_coil n/a 337 364
disorder n/a 367 368
disorder n/a 385 407
low_complexity n/a 385 397

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession D3ZZT6. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEPESEPASV EVPAGRVLSA SELRAARSRS QKLPQRSHGP KDFLPDGSEA
50
51
QAERLRLCRQ ELWQLLAEER VERLGSLVAA EWRPEEGFVE LTSPAGKFWQ
100
101
TMGYSEEGRQ RLHPEEALYL LECGSIQLFY QDLPLSIQEA YQLLLTEDTL
150
151
SFLQYQVFSH LKRLGYVVRR FQLSSVVSPY ERQLNLDGYA QCLEDGSGKR
200
201
KRSSSCRSVN KKAKALQNSL PPVSLADSSP PACDQSSPYP EEKPRDSSPE
250
251
QGSELPMQFL GSPEPCPDPG REDAGCDQES DKIENGAKGT PKPRWNFERI
300
301
SFPNMASDSR HTLLPAPAPE LLPVNVIGRG TDAESWCQKL NQRREKLSRR
350
351
DREQQAEVRQ FREDVNADPE VQGCSTWQEY KELLRRRQMQ RSQPRPPHLW
400
401
GQSVTPLLNP DTADSPAAVL QRISVLQTTH LADGGYRLLE KSGGLEISFD
450
451
VYQADAVATF RKNSPGKPYV RMCISGFDEP VPDLCSLKRL TYQSGDVPLI
500
501
FALVDHGDIS FYSFRDFTLP QDLGH                           
525
 

Show the unformatted sequence.

Checksums:
CRC64:CB204592C9A2A0C5
MD5:6a11f9f9572e6ca458b83d4150466e3d

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;