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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: LARA_THETC (D9TQ02)

Summary

This is the summary of UniProt entry LARA_THETC (D9TQ02).

Description: Lactate racemase {ECO:0000303|PubMed:24710389}
Source organism: Thermoanaerobacterium thermosaccharolyticum (strain ATCC 7956 / DSM 571 / NCIMB 9385 / NCA 3814 / NCTC 13789 / WDCM 00135 / 2032) (Clostridium thermosaccharolyticum) (NCBI taxonomy ID 580327)
Length: 426 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam Lar_N 8 213
disorder n/a 342 346

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession D9TQ02. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MANIEIPYGK SKLAFDLPDE RIQGILRSKA GSYKVNMSEE DIVKRALENP
50
51
IGTKRLQDLA EGKKNIVIIT SDHTRPVPSR ITLPLLLDEI RKKNKSANVK
100
101
ILIATGFHRG TTLQEMKAKF GEDLVENEQF VVHDSRNSEN MELIGTLPSG
150
151
GKLEINKLAV EADLLVAEGF IEPHFFAGFS GGRKSILPGI ASVQCILANH
200
201
CSEFIKNPYA RTGVLENNPI HRDMIYAAKK ANLAFILNVV IDSSHKIVNA
250
251
FAGHSEKAHL KGCEFVSEIA TVNAKPADIV ITSNGGYPLD QNIYQSVKGM
300
301
TAGEAACKDG GVIIIAAECA DGHGGEGFYR WFKESKDPQD VMNKILSRGR
350
351
DETLPDQWEA QILARILINH KVIMVTDSKN YEYVKDMFMT PAKDLGEALK
400
401
IAESIVNNDS KINVIPDGVS VIVREK                          
426
 

Show the unformatted sequence.

Checksums:
CRC64:FBC204F4B8CC0212
MD5:80a56106b8b28a475f796d25629de8bb

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Lar_N 8 - 213 2YJG A 8 - 213 Show 3D Structure View in InterPro
B 8 - 213 Show 3D Structure View in InterPro
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The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;