Summary
This is the summary of UniProt entry E7F998_DANRE (E7F998).
| Description: | Serine/threonine-protein kinase receptor {ECO:0000256|RuleBase:RU361271} |
| Source organism: |
Danio rerio (Zebrafish) (Brachydanio rerio)
(NCBI taxonomy ID
7955)
|
| Length: | 645 amino acids |
| Reference Proteome: |
|
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
Download the data used to generate the domain graphic in JSON format.
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| Source | Domain | Start | End |
|---|---|---|---|
| sig_p | n/a | 1 | 15 |
| Pfam | ecTbetaR2 | 16 | 125 |
| low_complexity | n/a | 113 | 126 |
| Pfam | ecTbetaR2 | 137 | 242 |
| transmembrane | n/a | 254 | 279 |
| disorder | n/a | 313 | 314 |
| Pfam | PK_Tyr_Ser-Thr | 328 | 618 |
| disorder | n/a | 633 | 645 |
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession E7F998. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MFSGVSAALL RTADLRICSS CKPHPVNCVS NQCFSNCSVS TECVNEQDVC
50 51
AAVWWRDAGL VMVETLCHDP LKPMLGVMVE DILISECVLQ EQNIHGRHLR
100 101
VCSCTGDQCN QNLLLRKLTE EEKLSKTNSS SGFRLKQNCK FCDVESSVCN
150 151
ASGVCESACG INSICETPDE VCASAWRSNG GNSSIETVCH NPALLFHGHN
200 201
LTDSQSRVCQ MRRVEEDLYI CSCNDEECND RLFFNHDLKQ YPGVQFDPPS
250 251
ESSWFSLAPV LISVFVLIPI VLLSVFYCYH ISQHKLKLPN KKSLDSERCN
300 301
IFMNPEEHSD SSSINANSLN HNTELLPIQL DRVVGKGRFA DVYKAKLKQS
350 351
ADSFQTVAVK IFPYEEFSSW KSEWQIFSDV ELRHENVLQF LTAEERTAER
400 401
QYWLITAYHE RGNLQELLAL QVIGWEEMCR LGVSLARGVA HLHSDRTPCG
450 451
RAKVSIAHRD LKSSNVLVKS DWSCCVCDFG LSLRLDSCLS PEELANSGQV
500 501
GTARYMAPEV LESRMDLENT ESFKQADVYS MALVLWEIMS RCSATGDVRD
550 551
YEPPFGKLKG HPCVESMKDD VIRDRLRPEI PTSWSKHAGV HHLSSTIEEC
600 601
WDHDPEARLT AQCVVERFDD IINSDVILPI SPDTKSAGDS GIQEM
645
Show the unformatted sequence. |
| Checksums: |
CRC64:2F95362422DC663A
MD5:6c6827404da00f05f81f5e6e1252aaf2
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.
AlphaFold Structure Prediction
The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.
Model confidence scale
| Very High (pLDDT > 90) | |
| Confident (90 > pLDDT > 70) | |
| Low (70 > pLDDT > 50) | |
| Very Low (pLDDT < 50) |
