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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: F1QAH4_DANRE (F1QAH4)

Summary

This is the summary of UniProt entry F1QAH4_DANRE (F1QAH4).

Description: TGF-beta receptor type-2 {ECO:0000256|PIRNR:PIRNR037393}
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 590 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
sig_p n/a 1 21
Pfam ecTbetaR2 28 138
transmembrane n/a 143 168
low_complexity n/a 143 161
disorder n/a 177 188
disorder n/a 216 217
disorder n/a 219 222
Pfam Pkinase 234 531
disorder n/a 491 492
disorder n/a 541 567
disorder n/a 577 578
disorder n/a 585 590

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession F1QAH4. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MGLWTRTSAL LCCFCLLQVQ SLSPIKTNLC KWCDHSSPVC EDNVCMSNCS
50
51
LTSYCFLAEE VCVAIWKKDN VSVSVRTLCY DPQHMLENIM LANYSSKECL
100
101
MSPHPSEDGL LFICSCVGDQ ECNDRLIFDK GPNGFSKLKS KDVIPVVVIS
150
151
LVPPLLVAVI ATMAFYLYRT RQPGKKPKEW GPRRTHYQSL DPAEGQANGI
200
201
DFSAKRPSLS DDINSEMSST CANNLNHNTE QLPIQLEALV GKGRFAEVWR
250
251
ARLSHNESGQ YETVAVKIFP AVEYSSWCNE RAIFSDANLK HENVVQFLTA
300
301
EERGGTSATS QRQYWLIMAY YNMGNLQDFL VGNILTWAEL CSLAGSVARG
350
351
LAHLHSDTTP CGIQKVPIAH RDLKSSNIVL KNQSECVLCD FGLALRLDLS
400
401
LTVDDFANSG QVGTARYMAP EVLESRVNLE DLESFKQIDI YSMALVMWEM
450
451
VSRCDVIGEV KSYEPPFGSK VCEQPCVDSM RDLVLRDRGR PDIPDSWTTH
500
501
SGMQLLCATI TECWDHDPEA RLTAHCVVER FNTLAQEELE NSICTHTPST
550
551
PPTEDQTPTL PSHPPCTDHS ADICPHVTAD IVSSRQHSQV           
590
 

Show the unformatted sequence.

Checksums:
CRC64:C26873EED001328F
MD5:69eeeb29b3460646b377474972222529

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;