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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: F1QKF4_DANRE (F1QKF4)

Summary

This is the summary of UniProt entry F1QKF4_DANRE (F1QKF4).

Description: TGF-beta receptor type-2 {ECO:0000256|PIRNR:PIRNR037393}
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 556 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
sig_p n/a 1 21
Pfam ecTbetaR2 39 148
transmembrane n/a 147 172
low_complexity n/a 147 168
disorder n/a 183 192
low_complexity n/a 186 197
low_complexity n/a 209 217
disorder n/a 215 222
Pfam PK_Tyr_Ser-Thr 232 524
disorder n/a 481 485
disorder n/a 535 536
disorder n/a 548 552

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession F1QKF4. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MERYQLSVLC WWTFLISTVV DWRGVDGNNP FYRPYRIPQL CKFCDVLESN
50
51
CNGKDTCESN CSITSICESP DEICVAIWRQ SDDNNTIETL CHNPTVPLYG
100
101
IMVENNNNTK CEMKKRISNS GPFHICSCNE VECNDMLLFK LPTNNQVVLV
150
151
ILVSLLPLLV LAVLVIASFY WYRMYRRRKL DEWETKKPSK HKGPKGPLDC
200
201
SDACAIMMDD DRSDSSSTHA NNINHNMDPL PIELDLQVGK GRFAEVYKAK
250
251
LRQSPSEQFE TVAVKIFPYE EYASWKNEKD IFQDIDLKHE NILHFLTAEE
300
301
RKVEKQYWLI TAFHPRGNLQ EYLMRHLLSW EDLRLLGSSL ASGVAHLHSD
350
351
HTPCGRPKVP IVHRDLKSSN ILVKNDLTCC LCDFGLGLRL DNSLSVDELA
400
401
NSGQVGTARY MAPEVLESRI NLENIESFKQ TDVYSMALVL WEITSRCNAI
450
451
GEVKDYEPPF GSKVREHPCV ESMKDNVLRD RGRPEIPSSW MKHQGVAAVC
500
501
ATINECWDHD PEARLTAQCV AERFNEMDDD LDKLSTCSSS EEKIPEDCAV
550
551
SVSDDK                                                
556
 

Show the unformatted sequence.

Checksums:
CRC64:DD68FD49C422A4D0
MD5:e4684c902aa59f94fef53e062c204ffd

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;