!!

Powering down the Pfam website
On October 5th, we will start redirecting the traffic from Pfam (pfam.xfam.org) to InterPro (www.ebi.ac.uk/interpro). The Pfam website will be available at legacy.pfam.xfam.org until January 2023, when it will be decommissioned. You can read more about the sunset period in our blog post.

Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: F1QYZ6_DANRE (F1QYZ6)

Summary

This is the summary of UniProt entry F1QYZ6_DANRE (F1QYZ6).

Description: Pyruvate carboxylase {ECO:0000256|ARBA:ARBA00013057, ECO:0000256|PIRNR:PIRNR001594}
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 1181 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
Pfam Biotin_carb_N 38 148
Pfam CPSase_L_D2 153 362
low_complexity n/a 200 210
coiled_coil n/a 209 229
Pfam Biotin_carb_C 377 485
disorder n/a 391 395
disorder n/a 517 518
disorder n/a 521 522
low_complexity n/a 524 535
Pfam HMGL-like 565 839
low_complexity n/a 688 705
low_complexity n/a 778 793
Pfam PYC_OADA 863 1063
Pfam Biotin_lipoyl 1112 1179

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession F1QYZ6. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MLLHLGGSRA KTGILFIRRA GLFCRSAHLS SQTLEYHPIK KVMVANRGEI
50
51
AIRVFRACTE LGIRTVAVYS EQDTGQMHRQ KADEAYLIGR GLSPVAAYLH
100
101
IPDIIKVAKE NNVDAIHPGY GFLSERADFA QACAEAGVRF IGPSPEVVRK
150
151
MGDKVEARAL AIKAGVPVVP GTDAPISCLQ EAQEFAKTYD FPIIFKAAYG
200
201
GGGRGMRVVR NYEELEENYQ RAYSEALAAF GNGALFVEKF IEKPRHIEVQ
250
251
ILGDKYGNVI HLYERDCSIQ RRHQKVVEIA PAAHLDSHLR DRLTLDSVNL
300
301
AKQVGYENAG TVEFLVDKHG KHYFIEVNSR LQVEHTVTEE ITDVDLVHAQ
350
351
LRVCEGRSLP ELGLEQDKIQ INGCAIQCRV TTEDPSRGFQ PDTGRIEVFR
400
401
SGEGMGIRLD SASAFQGAII SPHYDSLLVK VIASGKDLPT AATKMHRALT
450
451
EFRVRGVKTN IPFLQNVLSN SQFLYATVDT QFIDENQNLF NLKPTQNRAQ
500
501
KLLHYLGHVM VNGPMTPIPV KAKPSPVDPV IPSVSLGEPP LGFREVLLRE
550
551
GPEGFARAIR QHQGLLLMDT TFRDAHQSLL ATRVRTHDLK KIAPYVSHNF
600
601
SNLFSLENWG GATFDVAMRF LSECPWKRLQ ELRALIPNVP FQMLLRGANA
650
651
VGYTNYPDNA VFKFCEVAKE NGMDIFRVFD SLNYIPNMLL GMEAAGAAGG
700
701
VVEAAISYTG DVSDPMRQKY SLDYYLKLAD ELVKAGTHIL SIKDMAGLLK
750
751
PQASRLLIEA LRDRFPDIPI HVHTHDTAGA GVAAMLACAQ AGADIVDVAV
800
801
DSMAGMTSQP SMGAIVACTK GTKLDTGISL DKVFDYSEYW EVARGLYAPF
850
851
DCTATMKSGN ADVYENEIPG GQYTNLHFQA HSMGLGNKFK EVKKAYTEAN
900
901
KLLGDLIKVT PSSKIVGDLA QFMVQNSLSL AEVEKRADEL SFPLSVVEFL
950
951
QGHIGIPHGG FPEPFRSKVL KSLPRIEGRP GASLPPMDFE ALESGLRAAH
1000
1001
GDEITPEDVM SAAMYPKVFQ EFKEFTSTFG PVDCLNTRLF LDGPKIAEEF
1050
1051
QVELERGKIL HIKALALGDL NKSGQREVFF ELNGQLRSVL VKDTAAMKEM
1100
1101
HFHPKALKDV RGQVGAPMPG KVVEVKVKAG QKVEKGQPLC VLSAMKMETV
1150
1151
VNSPISGIIS KVHVNADSSL EGEDLILEIT E                    
1181
 

Show the unformatted sequence.

Checksums:
CRC64:CCB6C5B35218A32D
MD5:9543e1eea638f3638359ad87fe380e8f

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;