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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PYCB_METTH (O27179)

Summary

This is the summary of UniProt entry PYCB_METTH (O27179).

Description: Pyruvate carboxylase subunit B EC=6.4.1.1
Source organism: Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum) (NCBI taxonomy ID 187420)
Length: 568 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
Pfam HMGL-like 3 270
Pfam PYC_OADA 292 481
disorder n/a 332 333
disorder n/a 384 387
disorder n/a 401 402
disorder n/a 407 408
disorder n/a 414 416
low_complexity n/a 414 425
disorder n/a 444 466
low_complexity n/a 444 459
disorder n/a 482 484
disorder n/a 488 501
Pfam Biotin_lipoyl 500 567
disorder n/a 543 552

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O27179. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKGIKVVETA FRDAHQSLLA TRLRTRDMTP IAEEMDRVGF FSLEAWGGAT
50
51
FDTCIRYLNE DPWERLRELK EHVKRTPIQM LLRGQNLVGY KHYPDDIVRK
100
101
FIEKSYENGV DVFRIFDALN DIRNMEYAIK VAREQEAHVQ GVICYTISPY
150
151
HTLESYVDFA RELEALECDS VAIKDMAGLI SPHDAYELVR ALKEETDLMV
200
201
NLHCHCTSGM TPMSYYAACE AGVDILDTAI SPLSWGASQP PTESIVAALR
250
251
DTPYDTGLDL EILKNIKKYF EEIRKKYSSI LDPIAEQIDT DVLIYQIPGG
300
301
MLSNLVAQLK EQNALDRYEE VLEEMPRVRK DMGYPPLVTP TSQIVGIQAV
350
351
MNVLSGERYS MVTNEVKDYF RGLYGRPPAP LNEEVARKVI GDEKPIDCRP
400
401
ADILKPQYDE CRRKGEEMGI IEKEEDILTL ALYPAIAPKF LRGEIEEEPL
450
451
EPPAEEMAPT GEVPTVFHVE VDGDEFEVKV VPTGYMTIEE AEPEPVDVEG
500
501
AVKSTMQGMV VKLKVSEGDQ VNAGDVVAVV EAMKMENDIQ TPHGGVVEKI
550
551
YTAEGEKVET GDIIMVIK                                   
568
 

Show the unformatted sequence.

Checksums:
CRC64:D328715AB0328DBB
MD5:e4d26de72132a157b4ef7fea68d70e5d

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;