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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: IF6_METTH (O27648)

Summary

This is the summary of UniProt entry IF6_METTH (O27648).

Description: Translation initiation factor 6 {ECO:0000255|HAMAP-Rule:MF_00032}
Source organism: Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum) (NCBI taxonomy ID 187420)
Length: 222 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam eIF-6 4 218
disorder n/a 204 205

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O27648. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MIRRINLSGN PNLGVYISVT DSVALIPQNT PEKFEGVLRE ALEVEVLKVS
50
51
ISGSSLNGAL AVGNSNGFVV SNQAMDREID ALAAAGVEAV RIPERFTAVG
100
101
NLVLANDNGA VASPLLSDDA LQVIGDVLEV DVKVSTLAGL NIVGSMGAAT
150
151
NRGALLNPQA SSEEIGIIED TLGVEADVGT VNHGVTLIGA CSVANSNGVL
200
201
VGEETTGPEL ARIEEALGFL EG                              
222
 

Show the unformatted sequence.

Checksums:
CRC64:B86780BEC5C82533
MD5:4f52ba19cce35213411ec9e7bf999cbd

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
eIF-6 4 - 218 4ADX I 4 - 218 Show 3D Structure View in InterPro
×

The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;