!!

Powering down the Pfam website
On October 5th, we will start redirecting the traffic from Pfam (pfam.xfam.org) to InterPro (www.ebi.ac.uk/interpro). The Pfam website will be available at legacy.pfam.xfam.org until January 2023, when it will be decommissioned. You can read more about the sunset period in our blog post.

Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: AK2_BACSU (P08495)

Summary

This is the summary of UniProt entry AK2_BACSU (P08495).

Description: Aspartokinase 2 EC=2.7.2.4
Source organism: Bacillus subtilis (strain 168) (NCBI taxonomy ID 224308)
Length: 408 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
Pfam AA_kinase 2 230
low_complexity n/a 154 168
disorder n/a 233 240
low_complexity n/a 265 283
Pfam ACT 274 328
Pfam ACT_7 333 397

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P08495. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MGLIVQKFGG TSVGSVEKIQ NAANRAIAEK QKGHQVVVVV SAMGKSTDEL
50
51
VSLAKAISDQ PSKREMDMLL ATGEQVTISL LSMALQEKGY DAVSYTGWQA
100
101
GIRTEAIHGN ARITDIDTSV LADQLEKGKI VIVAGFQGMT EDCEITTLGR
150
151
GGSDTTAVAL AAALKADKCD IYTDVPGVFT TDPRYVKSAR KLEGISYDEM
200
201
LELANLGAGV LHPRAVEFAK NYQVPLEVRS STETEAGTLI EEESSMEQNL
250
251
IVRGIAFEDQ ITRVTIYGLT SGLTTLSTIF TTLAKRNINV DIIIQTQAED
300
301
KTGISFSVKT EDADQTVAVL EEYKDALEFE KIETESKLAK VSIVGSGMVS
350
351
NPGVAAEMFA VLAQKNILIK MVSTSEIKVS TVVSENDMVK AVESLHDAFE
400
401
LSKHPSAV                                              
408
 

Show the unformatted sequence.

Checksums:
CRC64:2E7189F938F97120
MD5:879a4571ed42d63fcdd3fb30b4c07288

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;