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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: CD68_HUMAN (P34810)

Summary

This is the summary of UniProt entry CD68_HUMAN (P34810).

Description: Macrosialin
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 354 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
sig_p n/a 1 19
low_complexity n/a 3 21
disorder n/a 11 12
disorder n/a 14 161
low_complexity n/a 37 79
low_complexity n/a 75 84
low_complexity n/a 103 117
low_complexity n/a 136 153
Pfam Lamp 155 303
disorder n/a 193 195
low_complexity n/a 274 285
transmembrane n/a 320 344
low_complexity n/a 320 340

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P34810. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MRLAVLFSGA LLGLLAAQGT GNDCPHKKSA TLLPSFTVTP TVTESTGTTS
50
51
HRTTKSHKTT THRTTTTGTT SHGPTTATHN PTTTSHGNVT VHPTSNSTAT
100
101
SQGPSTATHS PATTSHGNAT VHPTSNSTAT SPGFTSSAHP EPPPPSPSPS
150
151
PTSKETIGDY TWTNGSQPCV HLQAQIQIRV MYTTQGGGEA WGISVLNPNK
200
201
TKVQGSCEGA HPHLLLSFPY GHLSFGFMQD LQQKVVYLSY MAVEYNVSFP
250
251
HAAQWTFSAQ NASLRDLQAP LGQSFSCSNS SIILSPAVHL DLLSLRLQAA
300
301
QLPHTGVFGQ SFSCPSDRSI LLPLIIGLIL LGLLALVLIA FCIIRRRPSA
350
351
YQAL                                                  
354
 

Show the unformatted sequence.

Checksums:
CRC64:69E68D69EDE8EFB0
MD5:4adf59270764fe0ae91244785dfad70d

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;