Summary
This is the summary of UniProt entry AF9_HUMAN (P42568).
Description: | Protein AF-9 {ECO:0000305} |
Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
|
Length: | 568 amino acids |
Reference Proteome: |
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Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
Download the data used to generate the domain graphic in JSON format.
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Source | Domain | Start | End |
---|---|---|---|
Pfam | YEATS | 27 | 108 |
disorder | n/a | 116 | 123 |
disorder | n/a | 130 | 308 |
low_complexity | n/a | 149 | 190 |
low_complexity | n/a | 226 | 246 |
low_complexity | n/a | 254 | 265 |
low_complexity | n/a | 290 | 306 |
low_complexity | n/a | 299 | 313 |
disorder | n/a | 318 | 498 |
low_complexity | n/a | 341 | 351 |
low_complexity | n/a | 371 | 395 |
low_complexity | n/a | 412 | 430 |
low_complexity | n/a | 437 | 453 |
low_complexity | n/a | 446 | 471 |
Pfam | AHD | 503 | 563 |
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession P42568. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
Sequence: | 1
MASSCAVQVK LELGHRAQVR KKPTVEGFTH DWMVFVRGPE HSNIQHFVEK
50 51
VVFHLHESFP RPKRVCKDPP YKVEESGYAG FILPIEVYFK NKEEPRKVRF
100 101
DYDLFLHLEG HPPVNHLRCE KLTFNNPTED FRRKLLKAGG DPNRSIHTSS
150 151
SSSSSSSSSS SSSSSSSSSS SSSSSSSSSS SSSSSSSSSS TSFSKPHKLM
200 201
KEHKEKPSKD SREHKSAFKE PSRDHNKSSK ESSKKPKENK PLKEEKIVPK
250 251
MAFKEPKPMS KEPKPDSNLL TITSGQDKKA PSKRPPISDS EELSAKKRKK
300 301
SSSEALFKSF SSAPPLILTC SADKKQIKDK SHVKMGKVKI ESETSEKKKS
350 351
TLPPFDDIVD PNDSDVEENI SSKSDSEQPS PASSSSSSSS SFTPSQTRQQ
400 401
GPLRSIMKDL HSDDNEEESD EVEDNDNDSE MERPVNRGGS RSRRVSLSDG
450 451
SDSESSSASS PLHHEPPPPL LKTNNNQILE VKSPIKQSKS DKQIKNGECD
500 501
KAYLDELVEL HRRLMTLRER HILQQIVNLI EETGHFHITN TTFDFDLCSL
550 551
DKTTVRKLQS YLETSGTS
568
Show the unformatted sequence. |
Checksums: |
CRC64:0A020B7FB34132F9
MD5:ba05abf472c72920b0d36db229b3d33b
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.
The parts of the structure corresponding to the Pfam family are highlighted in blue.
Loading Structure Data
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.
AlphaFold Structure Prediction
The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.
Model confidence scale
Very High (pLDDT > 90) | |
Confident (90 > pLDDT > 70) | |
Low (70 > pLDDT > 50) | |
Very Low (pLDDT < 50) |