Summary
This is the summary of UniProt entry PYC_RAT (P52873).
| Description: | Pyruvate carboxylase, mitochondrial EC=6.4.1.1 |
| Source organism: |
Rattus norvegicus (Rat)
(NCBI taxonomy ID
10116)
|
| Length: | 1178 amino acids |
| Reference Proteome: |
|
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
Download the data used to generate the domain graphic in JSON format.
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| Source | Domain | Start | End |
|---|---|---|---|
| low_complexity | n/a | 7 | 18 |
| Pfam | Biotin_carb_N | 36 | 146 |
| Pfam | CPSase_L_D2 | 151 | 360 |
| low_complexity | n/a | 157 | 169 |
| Pfam | Biotin_carb_C | 375 | 483 |
| disorder | n/a | 389 | 392 |
| disorder | n/a | 442 | 443 |
| low_complexity | n/a | 512 | 538 |
| disorder | n/a | 515 | 516 |
| disorder | n/a | 519 | 520 |
| Pfam | HMGL-like | 563 | 837 |
| low_complexity | n/a | 689 | 703 |
| low_complexity | n/a | 787 | 799 |
| Pfam | PYC_OADA | 861 | 1061 |
| disorder | n/a | 861 | 862 |
| Pfam | Biotin_lipoyl | 1110 | 1177 |
| low_complexity | n/a | 1118 | 1134 |
| disorder | n/a | 1160 | 1161 |
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession P52873. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MLKFQTVRGG LRLLGVRRSS TAPVASPNVR RLEYKPIKKV MVANRGEIAI
50 51
RVFRACTELG IRTVAVYSEQ DTGQMHRQKA DEAYLIGRGL APVQAYLHIP
100 101
DIIKVAKENG VDAVHPGYGF LSERADFAQA CQDAGVRFIG PSPEVVRKMG
150 151
DKVEARAIAI AAGVPVVPGT NSPINSLHEA HEFSNTYGFP IIFKAAYGGG
200 201
GRGMRVVHSY EELEENYTRA YSEALAAFGN GALFVEKFIE KPRHIEVQIL
250 251
GDQYGNILHL YERDCSIQRR HQKVVEIAPA THLDPQLRSR LTSDSVKLAK
300 301
QVGYENAGTV EFLVDKHGKH YFIEVNSRLQ VEHTVTEEIT DVDLVHAQIH
350 351
VSEGRSLPDL GLRQENIRIN GCAIQCRVTT EDPARSFQPD TGRIEVFRSG
400 401
EGMGIRLDNA SAFQGAVISP HYDSLLVKVI AHGKDHPTAA TKMSRALAEF
450 451
RVRGVKTNIP FLQNVLNNQQ FLAGIVDTQF IDENPELFQL RPAQNRAQKL
500 501
LHYLGHVMVN GPTTPIPVKV SPSPVDPIVP VVPIGPPPAG FRDILLREGP
550 551
EGFARAVRNH QGLLLMDTTF RDAHQSLLAT RVRTHDLKKI APYVAHNFNN
600 601
LFSIENWGGA TFDVAMRFLY ECPWRRLQEL RELIPNIPFQ MLLRGANAVG
650 651
YTNYPDNVVF KFCEVAKENG MDVFRIFDSL NYLPNMLLGM EAAGSAGGVV
700 701
EAAISYTGDV ADPSRTKYSL EYYMGLAEEL VRAGTHILCI KDMAGLLKPA
750 751
ACTMLVSSLR DRFPDLPLHI HTHDTSGSGV AAMLACAQAG ADVVDVAVDS
800 801
MSGMTSQPSM GALVACTKGT PLDTEVPLER VFDYSEYWEG ARGLYAAFDC
850 851
TATMKSGNSD VYENEIPGGQ YTNLHFQAHS MGLGSKFKEV KKAYVEANQM
900 901
LGDLIKVTPS SKIVGDLAQF MVQNGLSRAE AEAQAEELSF PRSVVEFLQG
950 951
YIGIPHGGFP EPFRSKVLKD LPRIEGRPGA SLPPLNLKEL EKDLIDRHGE
1000 1001
EVTPEDVLSA AMYPDVFAQF KDFTATFGPL DSLNTRLFLQ GPKIAEEFEV
1050 1051
ELERGKTLHI KALAVSDLNR AGQRQVFFEL NGQLRSILVK DTQAMKEMHF
1100 1101
HPKALKDVKG QIGAPMPGKV IDVKVAAGAK VVKGQPLCVL SAMKMETVVT
1150 1151
SPMEGTIRKV HVTKDMTLEG DDLILEIE
1178
Show the unformatted sequence. |
| Checksums: |
CRC64:782CDFEF3380DB2D
MD5:c7d189bc27a422c1293e1d314fc7e1b8
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.
AlphaFold Structure Prediction
The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.
Model confidence scale
| Very High (pLDDT > 90) | |
| Confident (90 > pLDDT > 70) | |
| Low (70 > pLDDT > 50) | |
| Very Low (pLDDT < 50) |
