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7  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: DDAH1_BOVIN (P56965)

Summary

This is the summary of UniProt entry DDAH1_BOVIN (P56965).

Description: N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 EC=3.5.3.18
Source organism: Bos taurus (Bovine) (NCBI taxonomy ID 9913)
Length: 285 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 36 37
Pfam ADI 66 224
disorder n/a 94 97
disorder n/a 99 103
coiled_coil n/a 102 122

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P56965. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MASLGHPATF GRATHVVVRA LPESLAQQAL RRTKGDEVDF ARAERQHQLY
50
51
VGVLGSKLGL QVVQLPADES LPDCVFVEDV AVVCEETALI TRPGAPSRRK
100
101
EADMMKEALE KLQLNIVEMK DENATLDGGD VLFTGREFFV GLSKRTNQRG
150
151
AEILADTFKD YAVSTVPVVD ALHLKSFCSM AGPNLIAIGS SESAQKALKI
200
201
MQQMSDHRYD KLTVPDDTAA NCIYLNIPSK GHVLLHRTPE EYPESAKVYE
250
251
KLKDHMLIPV SNSELEKVDG LLTCSSVLIN KKVDS                
285
 

Show the unformatted sequence.

Checksums:
CRC64:65C5C032EE513CE5
MD5:6a086917b401019be32038c1dc38d1cc

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
ADI 66 - 224 2C6Z A 65 - 223 Show 3D Structure View in InterPro
2CI1 A 65 - 223 Show 3D Structure View in InterPro
2CI3 A 65 - 223 Show 3D Structure View in InterPro
2CI4 A 65 - 223 Show 3D Structure View in InterPro
2CI5 A 65 - 223 Show 3D Structure View in InterPro
B 65 - 223 Show 3D Structure View in InterPro
2CI6 A 65 - 223 Show 3D Structure View in InterPro
2CI7 A 65 - 223 Show 3D Structure View in InterPro
×

The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;