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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: RSME_MYCTU (P9WGX1)

Summary

This is the summary of UniProt entry RSME_MYCTU (P9WGX1).

Description: Ribosomal RNA small subunit methyltransferase E EC=2.1.1.193
Source organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (NCBI taxonomy ID 83332)
Length: 262 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam PUA_4 20 67
low_complexity n/a 57 69
low_complexity n/a 65 82
Pfam Methyltrans_RNA 74 241
low_complexity n/a 128 145
low_complexity n/a 159 179
low_complexity n/a 229 245

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P9WGX1. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MVAMLFYVDT LPDTGAVAVV DGDEGFHAAT VRRIRPGEQL VLGDGVGRLA
50
51
RCVVEQAGRG GLRARVLRRW SVPPVRPPVT VVQALPKSER SELAIELATE
100
101
AGADAFLAWQ AARCVANWDG ARVDKGLRRW RAVVRSAARQ SRRARIPPVD
150
151
GVLSTPMLVQ RVREEVAAGA AVLVLHEEAT ERIVDIAAAQ AGSLMLVVGP
200
201
EGGIAPDELA ALTDAGAVAV RLGPTVLRTS TAAAVALGAV GVLTSRWDAS
250
251
ASDCEYCDVT RR                                         
262
 

Show the unformatted sequence.

Checksums:
CRC64:27F970FBF989B2BF
MD5:5fc59bc3bbd71181c5d1ff334af3b203

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Methyltrans_RNA 74 - 241 4L69 A 74 - 241 Show 3D Structure View in InterPro
PUA_4 20 - 67 4L69 A 20 - 67 Show 3D Structure View in InterPro
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The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;