Summary
This is the summary of UniProt entry RPA49_YEAST (Q01080).
| Description: | DNA-directed RNA polymerase I subunit RPA49 |
| Source organism: |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
(NCBI taxonomy ID
559292)
|
| Length: | 415 amino acids |
| Reference Proteome: |
|
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
Download the data used to generate the domain graphic in JSON format.
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| Source | Domain | Start | End |
|---|---|---|---|
| Pfam | RNA_pol_I_A49 | 33 | 404 |
| disorder | n/a | 62 | 66 |
| low_complexity | n/a | 97 | 106 |
| disorder | n/a | 108 | 120 |
| disorder | n/a | 124 | 128 |
| disorder | n/a | 173 | 190 |
| low_complexity | n/a | 222 | 233 |
| low_complexity | n/a | 259 | 269 |
| disorder | n/a | 406 | 415 |
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q01080. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MSVKRSVSEI EIESVQDQPS VAVGSFFKGF RAPSDTTFDL YKKKKSEKDE
50 51
FVLHGENERL EYEGYTDSSS QASNQYVVGL FNPEKKSIQL YKAPVLVSKV
100 101
VSKSSKNLRG PKIKSKSDTR PSALRNALGE AFGTKKAKKA IADLERNRID
150 151
SDKLTDSAID IVDSVRTASK DLPTRAQLDE ITSNDRPTPL ANIDATDVEQ
200 201
IYPIESIIPK KELQFIRVSS ILKEADKEKK LELFPYQNNS KYVAKKLDSL
250 251
TQPSQMTKLQ LLYYLSLLLG VYENRRVNNK TKLLERLNSP PEILVDGILS
300 301
RFTVIKPGQF GRSKDRSYFI DPQNEDKILC YILAIIMHLD NFIVEITPLA
350 351
HELNLKPSKV VSLFRVLGAI VKGATVAQAE AFGIPKSTAA SYKIATMKVP
400 401
FKLPEMTRRG RGPRR
415
Show the unformatted sequence. |
| Checksums: |
CRC64:3D9BF05440D26021
MD5:edf9dda6592febeed30138b513d77055
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.
The parts of the structure corresponding to the Pfam family are highlighted in blue.
Loading Structure Data
AlphaFold Structure Prediction
The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.
Model confidence scale
| Very High (pLDDT > 90) | |
| Confident (90 > pLDDT > 70) | |
| Low (70 > pLDDT > 50) | |
| Very Low (pLDDT < 50) |
