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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: Q0E9E2_DROME (Q0E9E2)

Summary

This is the summary of UniProt entry Q0E9E2_DROME (Q0E9E2).

Description: Pyruvate carboxylase {ECO:0000256|ARBA:ARBA00013057, ECO:0000256|PIRNR:PIRNR001594}
Source organism: Drosophila melanogaster (Fruit fly) (NCBI taxonomy ID 7227)
Length: 1197 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam Biotin_carb_N 38 148
Pfam CPSase_L_D2 153 362
low_complexity n/a 200 210
Pfam Biotin_carb_C 377 485
disorder n/a 391 393
disorder n/a 521 522
disorder n/a 538 542
disorder n/a 545 554
Pfam HMGL-like 581 856
low_complexity n/a 708 722
low_complexity n/a 782 794
low_complexity n/a 806 818
Pfam PYC_OADA 880 1079
low_complexity n/a 1000 1015
disorder n/a 1119 1131
Pfam Biotin_lipoyl 1129 1196

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q0E9E2. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MFIPAAQSAY RTLRKTQPRV RLNAIFKNGY SSKVEYKPIR SVLVANRGEI
50
51
AIRVFRACTE LGIKSVAVYS EQDKMHMHRQ KADESYIVGK GLPPVEAYLN
100
101
IPELIRVCKE NDVDAVHPGY GFLSERSDFA QAVIDAGLRF IGPSPEVVQK
150
151
MGDKVAARVA AIEAGVPIVP GTDGPVTTKE EALEFCKKHG LPVIFKAAYG
200
201
GGGRGMRVVR KMEDVEESFQ RASSEAKAAF GNGAMFIEKF IERPRHIEVQ
250
251
LLGDKAGNVV HLYERDCSVQ RRHQKVVEIA PAPRLPIEIR DKMTEAAVRL
300
301
ARHVGYENAG TVEFLCDESG NFYFIEVNAR LQVEHTVTEE ITGIDLVQSQ
350
351
IRVAEGMTLP ELGYTQDKIV PRGYAIQCRV TTEDPANDFQ PNTGRLEVFR
400
401
SGEGMGIRLD SASAYAGAII SPYYDSLLVK VISHASDLQS SASKMNRALR
450
451
EFRIRGVKTN IPFLLNVLEN QKFLHGVLDT YFIDEHPQLF KFKPSLNRAQ
500
501
KLLNYMGEVL VNGPQTPLAT TLKPALVSPH VPEVPLDLSP EAIEREERGE
550
551
AKVTEPPKGL REVLVCEGPE AFAKEVRNRK ELLLMDTTFR DAHQSLLATR
600
601
VRSHDLLKIS PYVTHKFNNL YSLENWGGAT FDVALRFLHE CPWERLEEMR
650
651
KRIPNIPFQM LLRGANAVGY TSYPDNVVYK FCELAVQTGM DIFRVFDSLN
700
701
YLPNLILGME AAGKAGGVVE AAISYTGDVS DPKRTKYDLK YYTNLADELV
750
751
KAGTHVLCIK DMAGLLKPES ARLLITAIRD KHPDIPIHIH THDTSGAGVA
800
801
SMLACANAGA DVVDVAVDSM SGMTSQPSMG AVVASLQGTP LDTNLDLRTV
850
851
SEYSAYWEQT RTLYAPFECT TTMRSGNADV YLNEIPGGQY TNLQFQAFSL
900
901
GLGDFFEDVK KAYREANLLL GDIIKVTPSS KVVGDLAQFM VQNDLTADQV
950
951
LERAEELSFP KSVVEYLQGS IGIPHGGFPE PLRSRVLKDM PRIEGRPGAE
1000
1001
LKDLDFDKLK KELQESHTCV TNRDVMSAAL YPQVTNDFLN FREKYGPVDK
1050
1051
LDTRIFLTGP KVGEEFDVPL ERGKTLSVKA LAVSADLKPN GIREVFFELN
1100
1101
GQLRAVHILD KEAVKEIHVH PKANKSNKSE VGAPMPGTVI DIRVKVGDKV
1150
1151
EKGQPLVVLS AMKMEMVVQS PLAGVVKKLE IANGTKLEGE DLIMIIE   
1197
 

Show the unformatted sequence.

Checksums:
CRC64:F095E0D880E721D2
MD5:03088370145028e2f7776b9b7e6c17f7

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;