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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PYC_BOVIN (Q29RK2)

Summary

This is the summary of UniProt entry PYC_BOVIN (Q29RK2).

Description: Pyruvate carboxylase, mitochondrial EC=6.4.1.1
Source organism: Bos taurus (Bovine) (NCBI taxonomy ID 9913)
Length: 1178 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
low_complexity n/a 10 26
Pfam Biotin_carb_N 36 146
Pfam CPSase_L_D2 151 360
low_complexity n/a 157 169
Pfam Biotin_carb_C 375 483
disorder n/a 389 393
disorder n/a 441 443
disorder n/a 487 488
disorder n/a 514 522
low_complexity n/a 521 540
disorder n/a 527 532
Pfam HMGL-like 563 837
low_complexity n/a 689 703
low_complexity n/a 785 799
Pfam PYC_OADA 861 1061
disorder n/a 932 933
disorder n/a 985 990
disorder n/a 993 996
disorder n/a 998 1001
disorder n/a 1003 1005
Pfam Biotin_lipoyl 1110 1177
disorder n/a 1160 1161

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q29RK2. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MLKFQTVRGS LRLLAIRRTS TATAASPNVR RLEYKPIKKV MVANRGEIAI
50
51
RVFRACTELG IRTVAVYSEQ DTGQMHRQKA DEAYLIGRGL APVQAYLHIP
100
101
DIIKVAKENN VDAVHPGYGF LSERADFAQA CQDAGVRFIG PSPEVVRKMG
150
151
DKVEARAIAI AAGVPVVPGT DAPITSLHEA HEFSNTYGFP IIFKAAYGGG
200
201
GRGMRVVHSY EELEENYTRA YSEALAAFGN GALFVEKFIE KPRHIEVQIL
250
251
GDQYGNILHL YERDCSIQRR HQKVVEIAPA AHLDPQLRTR LTSDSVKLAK
300
301
QVGYENAGTV EFLVDRHGKH YFIEVNSRLQ VEHTVTEEIT DVDLVHAQIH
350
351
VAEGRSLPDL GLRQENIRIN GCAIQCRVTT EDPARSFQPD TGRIEVFRSG
400
401
EGMGIRLDNA SAFQGAVISP HYDSLLVKVI AHGKDHPTAA TKMSRALAEF
450
451
RVRGVKTNIP FLQNVLNNQQ FLAGTVDTQF IDENPELFQL RPAQNRAQKL
500
501
LHYLGHVMVN GPTTPIPVKA SPSPTDPIVP VVPIGPPPTG FRDILLREGP
550
551
EGFARAVRNH EGLLLMDTTF RDAHQSLLAT RVRTHDLKKI SPYVAHSFNK
600
601
LFSIENWGGA TFDVAMRFLY ECPWRRLQEL RELVPNIPFQ MLLRGANAVG
650
651
YTNYPDNVVF KFCEVAKENG MDIFRVFDSL NYLPNLLLGM EAAGSAGGVV
700
701
EAAISYTGDV SDPSRTKYSL QYYMGLAEEL VRAGTHILCI KDMAGLLKPT
750
751
ACTMLVSSLR DRFPDLPLHI HTHDTSGAGV AAMLACAHAG ADVVDVAADS
800
801
MSGMTSQPSM GALVACTRGT PLDTGVPLER VFDYSEYWEG ARGLYAAFDC
850
851
TATMKSGNSD VYENEIPGGQ YTNLHFQAHS MGLGSKFKEV KKAYVEANQM
900
901
LGDLIKVTPS SKIVGDLAQF MVQNGLTRAE AEAQAEELSF PRSVVEFLQG
950
951
YIGIPHGGFP EPLRSKVLKD LPRVEGRPGA SLPPLDLQAL EKELTERHGE
1000
1001
EVTPEDVLSA AMYPDVFAHF KDFTATFGPL DSLNTRLFLQ GPKIAEEFEV
1050
1051
ELERGKTLHI KALAISDLNR AGQRQVFFEL NGQLRSILVK DTQAMKEMHF
1100
1101
HPKALKDVKG QIGAPMPGKV IDIKVAAGAK VTKGQPLCVL SAMKMETVVT
1150
1151
SPVEGTVRKV HVTKDMTLEG DDLILEIE                        
1178
 

Show the unformatted sequence.

Checksums:
CRC64:15DDD18BC7920D01
MD5:74970d4a3ad454105928970ba6ab137f

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;