!!

Powering down the Pfam website
On October 5th, we will start redirecting the traffic from Pfam (pfam.xfam.org) to InterPro (www.ebi.ac.uk/interpro). The Pfam website will be available at legacy.pfam.xfam.org until January 2023, when it will be decommissioned. You can read more about the sunset period in our blog post.

Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: Q501W9_DANRE (Q501W9)

Summary

This is the summary of UniProt entry Q501W9_DANRE (Q501W9).

Description: RNA polymerase I subunit E {ECO:0000313|Ensembl:ENSDARP00000054573}
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 413 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
Pfam RNA_pol_I_A49 30 400
disorder n/a 38 41
disorder n/a 48 52
disorder n/a 109 122
disorder n/a 144 148
transmembrane n/a 328 349
disorder n/a 404 413

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q501W9. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAATCSWKTC EETEQNTFIV KFSNGNVKNA EELDFTVFKH SNASNPRKKN
50
51
RRIVVADSDR LPYVGSNFGS GSLQSNNMCK YFVGVLDKQT MQMKVHSAQL
100
101
FNMLPVIPGE ATEAESENQP STFRDKVDAL IEAFGTNKQK RALSSRRLNA
150
151
VGNETLHQAV AQAASNIIDQ KGVEALRNEV IETEAQSDAA LFLPPCNANA
200
201
DKLEDVYPFD QLLTPNEFES LKEVGAKYAT LSSEDLQKMR DNHCPQTVLK
250
251
HLETLSKDEA DRDRQCRCAW YLSFVIRASL QKRISFKFGS DDGCPRIIIN
300
301
KVLKNFTVES FHNGSLRNTV SMSMRMKMAS YCLALLLHMG GQTANLTLLH
350
351
RDMSISENKM LEVAKAMGLT LSRQNALGKE GGLIEDEHRM VSLVLPLVHY
400
401
DRRTERKKRK RMN                                        
413
 

Show the unformatted sequence.

Checksums:
CRC64:89DCA2D398833AB6
MD5:914066b64cb4eee655c34926bf5154d8

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;