!!

Powering down the Pfam website
On October 5th, we will start redirecting the traffic from Pfam (pfam.xfam.org) to InterPro (www.ebi.ac.uk/interpro). The Pfam website will be available at legacy.pfam.xfam.org until January 2023, when it will be decommissioned. You can read more about the sunset period in our blog post.

Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: RPA49_DICDI (Q54FE8)

Summary

This is the summary of UniProt entry RPA49_DICDI (Q54FE8).

Description: DNA-directed RNA polymerase I subunit rpa49
Source organism: Dictyostelium discoideum (Slime mold) (NCBI taxonomy ID 44689)
Length: 375 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
Pfam RNA_pol_I_A49 39 369
disorder n/a 54 59
disorder n/a 144 146
coiled_coil n/a 151 171
low_complexity n/a 327 338

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q54FE8. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSNLTVNVIE EKNLGDNKPC VLKFSQGLPP LSFIEKEPEF ISMSTKNKRH
50
51
RVVLTNTDQL EYESEDKDSK YAKYAIGIFD KNTKQLKIVP TKIQTMNQSV
100
101
IGYTLTLDSS SVISREERYD KIKKLADSFG SKITKKKMQK MEMENVENLD
150
151
YEKTTKSIDA VKNELADIES NEKPFDLPDF DAETNDVRKI YNIEAILPPR
200
201
IFFGLNHQPF LDIISKTSEA PSYLPEYFKD QLKRFEDIKD EEKVVYNCKL
250
251
LTFMWYSMIL MKSKGGHEPL IKEGCTSEVI NFLVSIFGSK INHKKYNISQ
300
301
DDKLKIYNYL AIFALKLEDF QITDIKSLAQ SLSLTSSSFE KHFTRVGCKV
350
351
VRIGSEKRSV RLEAPLKLPK ARFSN                           
375
 

Show the unformatted sequence.

Checksums:
CRC64:5041E70A02CE2BA8
MD5:be826f3db4686447d87f89014d20bca2

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;