Summary
This is the summary of UniProt entry TGFR2_MOUSE (Q62312).
| Description: | TGF-beta receptor type-2 EC=2.7.11.30 |
| Source organism: |
Mus musculus (Mouse)
(NCBI taxonomy ID
10090)
|
| Length: | 592 amino acids |
| Reference Proteome: |
|
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
Download the data used to generate the domain graphic in JSON format.
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| Source | Domain | Start | End |
|---|---|---|---|
| disorder | n/a | 28 | 29 |
| disorder | n/a | 31 | 33 |
| Pfam | ecTbetaR2 | 74 | 184 |
| transmembrane | n/a | 185 | 214 |
| Pfam | PK_Tyr_Ser-Thr | 269 | 563 |
| disorder | n/a | 574 | 592 |
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q62312. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MGRGLLRGLW PLHIVLWTRI ASTIPPHVPK SDVEMEAQKD ASIHLSCNRT
50 51
IHPLKHFNSD VMASDNGGAV KLPQLCKFCD VRLSTCDNQK SCMSNCSITA
100 101
ICEKPHEVCV AVWRKNDKNI TLETVCHDPK LTYHGFTLED AASPKCVMKE
150 151
KKRAGETFFM CACNMEECND YIIFSEEYTT SSPDLLLVII QVTGVSLLPP
200 201
LGIAIAVIII FYCYRVHRQQ KLSPSWESSK PRKLMDFSDN CAIILEDDRS
250 251
DISSTCANNI NHNTELLPIE LDTLVGKGRF AEVYKAKLKQ NTSEQFETVA
300 301
VKIFPYEEYS SWKTEKDIFS DINLKHENIL QFLTAEERKT ELGKQYWLIT
350 351
AFHAKGNLQE YLTRHVISWE DLRKLGSSLA RGIAHLHSDH TPCGRPKMPI
400 401
VHRDLKSSNI LVKNDLTCCL CDFGLSLRLD PTLSVDDLAN SGQVGTARYM
450 451
APEVLESRMN LENVESFKQT DVYSMALVLW EMTSRCNAVG EVKDYEPPFG
500 501
SKVREHPCVE SMKDSVLRDR GRPEIPSFWL NHQGIQIVCE TLTECWDHDP
550 551
EARLTAQCVA ERFSELEHPE RLSGRSCSQE KIPEDGSLNT TK
592
Show the unformatted sequence. |
| Checksums: |
CRC64:1A12D58550921F5E
MD5:07492d3f5aadb9b9f5fd403accb170d6
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.
AlphaFold Structure Prediction
The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.
Model confidence scale
| Very High (pLDDT > 90) | |
| Confident (90 > pLDDT > 70) | |
| Low (70 > pLDDT > 50) | |
| Very Low (pLDDT < 50) |
