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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: SV2C_MOUSE (Q69ZS6)

Summary

This is the summary of UniProt entry SV2C_MOUSE (Q69ZS6).

Description: Synaptic vesicle glycoprotein 2C
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
Length: 727 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
disorder n/a 1 18
coiled_coil n/a 20 40
disorder n/a 21 97
low_complexity n/a 51 61
disorder n/a 99 129
Pfam Sugar_tr 117 428
low_complexity n/a 119 135
coiled_coil n/a 120 140
transmembrane n/a 152 177
transmembrane n/a 189 208
transmembrane n/a 220 237
transmembrane n/a 243 267
transmembrane n/a 279 301
transmembrane n/a 321 340
transmembrane n/a 436 454
Pfam Pentapeptide_4 495 573
Pfam MFS_1 564 725
transmembrane n/a 580 603
transmembrane n/a 610 629
transmembrane n/a 635 659
transmembrane n/a 671 692
transmembrane n/a 698 718
low_complexity n/a 707 716

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q69ZS6. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEDSYKDRTS LMKGAKDIAK EVKKQTVKKV NQAVDRAQDE YTQRSYSRFQ
50
51
DEEDDDDYYP PGETYSGEVN DDEGSSEATE GHDEEDEIYE GEYQGIPSTN
100
101
QGKDSIVSVG QPKGDEYKDR RELESERRAD EEELAQQYEL IIQECGHGRF
150
151
QWALFFVLGM ALMADGVEVF VVGFVLPSAE TDLCIPNSGS GWLGSIVYLG
200
201
MMVGAFFWGG LADKVGRKQS LLICMSVNGF FAFLSSFVQG YGFFLVCRLL
250
251
SGFGIGGAIP TVFSYFAEVL AREKRGEHLS WLCMFWMIGG IYASAMAWAI
300
301
IPHYGWSFSM GSAYQFHSWR VFVIVCALPC VSSVVALTFM PESPRFLLEV
350
351
GKHDEAWMIL KLIHDTNMRA RGQPEKVFTV NKIKTPKQID ELIEIESDTG
400
401
TWYRRCFVRI RTELYGIWLT FMRCFNYPVR ENTIKLTIVW FTLSFGYYGL
450
451
SVWFPDVIKH LQSDEYALLT RNVQKDKYAN FSINFTMENQ IHTGMEYENG
500
501
RFLGVKFKSV TFKDSVFKSC TFDDVTSVNT YFKNCTFIDT LFDNTDFEPY
550
551
KFIDSEFQNC SFLHNKTGCQ ITFDDDYSAY WIYFVNFLGT LAVLPGNIVS
600
601
ALLMDRIGRL TMLGGSMVLS GISCFFLWFG TSESMMIGML CLYNGLTISA
650
651
WNSLDVVTVE LYPTDRRATG FGFLNALCKA AAVLGNLIFG SLVSITKAIP
700
701
ILLASTVLVC GGLVGLRLPD TRTQVLM                         
727
 

Show the unformatted sequence.

Checksums:
CRC64:E1D78203D4E3183A
MD5:e8f1f13579e13d7d4f3c43d6d50637b6

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;