Summary
This is the summary of UniProt entry SV2B_HUMAN (Q7L1I2).
| Description: | Synaptic vesicle glycoprotein 2B |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
|
| Length: | 683 amino acids |
| Reference Proteome: |
|
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
Download the data used to generate the domain graphic in JSON format.
Show or hide the data used to generate the graphic in JSON format.
| Source | Domain | Start | End |
|---|---|---|---|
| disorder | n/a | 4 | 8 |
| disorder | n/a | 12 | 54 |
| disorder | n/a | 57 | 68 |
| disorder | n/a | 77 | 80 |
| disorder | n/a | 82 | 83 |
| disorder | n/a | 85 | 86 |
| Pfam | Sugar_tr | 97 | 416 |
| transmembrane | n/a | 109 | 132 |
| transmembrane | n/a | 152 | 170 |
| transmembrane | n/a | 177 | 194 |
| transmembrane | n/a | 200 | 224 |
| transmembrane | n/a | 236 | 258 |
| transmembrane | n/a | 278 | 297 |
| transmembrane | n/a | 391 | 411 |
| Pfam | Pentapeptide_4 | 452 | 528 |
| Pfam | MFS_1 | 519 | 681 |
| transmembrane | n/a | 536 | 559 |
| transmembrane | n/a | 566 | 586 |
| transmembrane | n/a | 592 | 613 |
| transmembrane | n/a | 625 | 648 |
| transmembrane | n/a | 654 | 674 |
| low_complexity | n/a | 658 | 672 |
Show or hide domain scores.
Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q7L1I2. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MDDYKYQDNY GGYAPSDGYY RGNESNPEED AQSDVTEGHD EEDEIYEGEY
50 51
QGIPHPDDVK AKQAKMAPSR MDSLRGQTDL MAERLEDEEQ LAHQYETIMD
100 101
ECGHGRFQWI LFFVLGLALM ADGVEVFVVS FALPSAEKDM CLSSSKKGML
150 151
GMIVYLGMMA GAFILGGLAD KLGRKRVLSM SLAVNASFAS LSSFVQGYGA
200 201
FLFCRLISGI GIGGALPIVF AYFSEFLSRE KRGEHLSWLG IFWMTGGLYA
250 251
SAMAWSIIPH YGWGFSMGTN YHFHSWRVFV IVCALPCTVS MVALKFMPES
300 301
PRFLLEMGKH DEAWMILKQV HDTNMRAKGT PEKVFTVSNI KTPKQMDEFI
350 351
EIQSSTGTWY QRWLVRFKTI FKQVWDNALY CVMGPYRMNT LILAVVWFAM
400 401
AFSYYGLTVW FPDMIRYFQD EEYKSKMKVF FGEHVYGATI NFTMENQIHQ
450 451
HGKLVNDKFT RMYFKHVLFE DTFFDECYFE DVTSTDTYFK NCTIESTIFY
500 501
NTDLYEHKFI NCRFINSTFL EQKEGCHMDL EQDNDFLIYL VSFLGSLSVL
550 551
PGNIISALLM DRIGRLKMIG GSMLISAVCC FFLFFGNSES AMIGWQCLFC
600 601
GTSIAAWNAL DVITVELYPT NQRATAFGIL NGLCKFGAIL GNTIFASFVG
650 651
ITKVVPILLA AASLVGGGLI ALRLPETREQ VLM
683
Show the unformatted sequence. |
| Checksums: |
CRC64:B9818120898F09E2
MD5:82f85d7ca15578effd88770f7252a320
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.
AlphaFold Structure Prediction
The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.
Model confidence scale
| Very High (pLDDT > 90) | |
| Confident (90 > pLDDT > 70) | |
| Low (70 > pLDDT > 50) | |
| Very Low (pLDDT < 50) |
