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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: SEN54_MOUSE (Q8C2A2)

Summary

This is the summary of UniProt entry SEN54_MOUSE (Q8C2A2).

Description: tRNA-splicing endonuclease subunit Sen54
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
Length: 525 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 17
low_complexity n/a 2 13
low_complexity n/a 16 30
disorder n/a 28 32
disorder n/a 34 46
Pfam tRNA_int_end_N2 63 130
low_complexity n/a 196 208
disorder n/a 203 204
low_complexity n/a 219 232
disorder n/a 231 258
disorder n/a 270 275
disorder n/a 277 285
disorder n/a 287 290
disorder n/a 294 301
disorder n/a 306 327
low_complexity n/a 314 324
disorder n/a 333 335
disorder n/a 338 345
disorder n/a 347 362
disorder n/a 385 405

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q8C2A2. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEPEPEPGSV EVPAGRVLSA SELRAARSRS QKLPQRSHGP KDFLPDGSEA
50
51
QAERLRLCRQ ELWQLLAEER VERLGSLVAA EWKPEEGFVE LTSPAGKFWQ
100
101
TMGYSEEGRQ RLHPEEALYL LECGSIQLFY QDLPLSIQEA YQLLLTEDTL
150
151
SFLQYQVFSH LKRLGYVVRR FQLSSVVSPY ERQLNLDGYA QCLEDGSGKR
200
201
KRSSSCRSVN KKPKVLQNSL PPVSLAASSS PACDQSSQYP EEKSQDSSPR
250
251
QGSELPLQFL GSSEPCSDLA REDVGCDRES HKIENGAKGT PKLRWNFEQI
300
301
SFPNMASDSR HTFLPAPAPE LLPANVIGRG TDAESWCQKL NQRREKLSRR
350
351
DREQQAVVQQ FREDVNADPE VRGCSSWQEY KELLQRRQTQ KSQPRPPHLW
400
401
GQSVTPLLDP DKADCPAAVL QHISVLQTTH LADGGYRLLE KSGGLQISFD
450
451
VYQADAVATF RKNSPGKPYV RMCISGFDDP VPDLCSLKCL TYQSGDVPLI
500
501
FALVDHGDIS FYSFRDFTLP RDLGH                           
525
 

Show the unformatted sequence.

Checksums:
CRC64:EBC3D92CFA647BF7
MD5:983d1fb3f353c411b1d33637027a9ab2

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;