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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: SRBD1_HUMAN (Q8N5C6)

Summary

This is the summary of UniProt entry SRBD1_HUMAN (Q8N5C6).

Description: S1 RNA-binding domain-containing protein 1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 995 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 9
disorder n/a 11 12
low_complexity n/a 17 40
disorder n/a 26 82
disorder n/a 85 86
disorder n/a 91 165
low_complexity n/a 109 123
low_complexity n/a 146 159
disorder n/a 176 177
disorder n/a 187 204
disorder n/a 210 212
Pfam Tex_N 218 401
coiled_coil n/a 261 288
disorder n/a 316 319
low_complexity n/a 326 341
Pfam Tex_YqgF 537 663
Pfam HHH_3 703 767
disorder n/a 801 805
Pfam HHH_9 821 898
Pfam S1 915 991

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q8N5C6. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSSLPRRAKV QVQDVVLKDE FSSFSELSSA SEEDDKEDSA WEPQKKVPRS
50
51
RKQPPPKESK PKRMPRVKKN APQISDGSEV VVVKEELNSS VAIADTALED
100
101
RKNKLDTVQT LKTAKTKQKC AAQPHTVRRT KKLKVEEETS KASNLEGESN
150
151
SSETPSTSTV WGGTCKKEEN DDDFTFGQSA LKKIKTETYP QGQPVKFPAN
200
201
ANSTKEEVEM NWDMVQVLSE RTNIEPWVCA NIIRLFNDDN TIPFIIRYRK
250
251
ELINNLDADS LREVQQTLEE LRAVAKKVHS TIQKIKKEGK MSECLLKAML
300
301
NCKTFEELEH VSAPYKTGSK GTKAQRARQL GLEGAARALL EKPGELSLLS
350
351
YIRPDVKGLS TLQDIEIGVQ HILADMIAKD KDTLDFIRNL CQKRHVCIQS
400
401
SLAKVSSKKV NEKDVDKFLL YQHFSCNIRN IHHHQILAIN RGENLKVLTV
450
451
KVNISDGVKD EFCRWCIQNR WRPRSFARPE LMKILYNSLN DSFKRLIYPL
500
501
LCREFRAKLT SDAEKESVMM FGRNLRQLLL TSPVPGRTLM GVDPGYKHGC
550
551
KLAIISPTSQ ILHTDVVYLH CGQGFREAEK IKTLLLNFNC STVVIGNGTA
600
601
CRETEAYFAD LIMKNYFAPL DVVYCIVSEA GASIYSVSPE ANKEMPGLDP
650
651
NLRSAVSIAR RVQDPLAELV KIEPKHIGVG MYQHDVSQTL LKATLDSVVE
700
701
ECVSFVGVDI NICSEVLLRH IAGLNANRAK NIIEWREKNG PFINREQLKK
750
751
VKGLGPKSFQ QCAGFIRINQ DYIRTFCSQQ TETSGQIQGV AVTSSADVEV
800
801
TNEKQGKKKS KTAVNVLLKP NPLDQTCIHP ESYDIAMRFL SSIGGTLYEV
850
851
GKPEMQQKIN SFLEKEGMEK IAERLQTTVH TLQVIIDGLS QPESFDFRTD
900
901
FDKPDFKRSI VCLEDLQIGT VLTGKVENAT LFGIFVDIGV GKSGLIPIRN
950
951
VTEAKLSKTK KRRSLGLGPG ERVEVQVLNI DIPRSRITLD LIRVL     
995
 

Show the unformatted sequence.

Checksums:
CRC64:BB286FB734708C55
MD5:c7041055b45003e112c850ffb0d1432e

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;