!!

Powering down the Pfam website
On October 5th, we will start redirecting the traffic from Pfam (pfam.xfam.org) to InterPro (www.ebi.ac.uk/interpro). The Pfam website will be available at legacy.pfam.xfam.org until January 2023, when it will be decommissioned. You can read more about the sunset period in our blog post.

Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PYC_BACSU (Q9KWU4)

Summary

This is the summary of UniProt entry PYC_BACSU (Q9KWU4).

Description: Pyruvate carboxylase EC=6.4.1.1
Source organism: Bacillus subtilis (strain 168) (NCBI taxonomy ID 224308)
Length: 1148 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
Pfam Biotin_carb_N 5 115
disorder n/a 119 120
Pfam CPSase_L_D2 120 328
disorder n/a 129 137
disorder n/a 146 148
Pfam Biotin_carb_C 346 454
disorder n/a 360 362
disorder n/a 511 515
Pfam HMGL-like 533 807
disorder n/a 783 789
disorder n/a 825 827
Pfam PYC_OADA 829 1029
disorder n/a 829 837
disorder n/a 841 843
disorder n/a 1067 1070
disorder n/a 1073 1077
Pfam Biotin_lipoyl 1078 1145
disorder n/a 1103 1105
disorder n/a 1123 1124
disorder n/a 1128 1129

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9KWU4. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSQQSIQKVL VANRGEIAIR IFRACTELNI RTVAVYSKED SGSYHRYKAD
50
51
EAYLVGEGKK PIDAYLDIEG IIDIAKRNKV DAIHPGYGFL SENIHFARRC
100
101
EEEGIVFIGP KSEHLDMFGD KVKAREQAEK AGIPVIPGSD GPAETLEAVE
150
151
QFGQANGYPI IIKASLGGGG RGMRIVRSES EVKEAYERAK SEAKAAFGND
200
201
EVYVEKLIEN PKHIEVQVIG DKQGNVVHLF ERDCSVQRRH QKVIEVAPSV
250
251
SLSPELRDQI CEAAVALAKN VNYINAGTVE FLVANNEFYF IEVNPRVQVE
300
301
HTITEMITGV DIVQTQILVA QGHSLHSKKV NIPEQKDIFT IGYAIQSRVT
350
351
TEDPQNDFMP DTGKIMAYRS GGGFGVRLDT GNSFQGAVIT PYYDSLLVKL
400
401
STWALTFEQA AAKMVRNLQE FRIRGIKTNI PFLENVAKHE KFLTGQYDTS
450
451
FIDTTPELFN FPKQKDRGTK MLTYIGNVTV NGFPGIGKKE KPAFDKPLGV
500
501
KVDVDQQPAR GTKQILDEKG AEGLANWVKE QKSVLLTDTT FRDAHQSLLA
550
551
TRIRSHDLKK IANPTAALWP ELFSMEMWGG ATFDVAYRFL KEDPWKRLED
600
601
LRKEVPNTLF QMLLRSSNAV GYTNYPDNVI KEFVKQSAQS GIDVFRIFDS
650
651
LNWVKGMTLA IDAVRDTGKV AEAAICYTGD ILDKNRTKYD LAYYTSMAKE
700
701
LEAAGAHILG IKDMAGLLKP QAAYELVSAL KETIDIPVHL HTHDTSGNGI
750
751
YMYAKAVEAG VDIIDVAVSS MAGLTSQPSA SGFYHAMEGN DRRPEMNVQG
800
801
VELLSQYWES VRKYYSEFES GMKSPHTEIY EHEMPGGQYS NLQQQAKGVG
850
851
LGDRWNEVKE MYRRVNDMFG DIVKVTPSSK VVGDMALYMV QNNLTEKDVY
900
901
EKGESLDFPD SVVELFKGNI GQPHGGFPEK LQKLILKGQE PITVRPGELL
950
951
EPVSFEAIKQ EFKEQHNLEI SDQDAVAYAL YPKVFTDYVK TTESYGDISV
1000
1001
LDTPTFFYGM TLGEEIEVEI ERGKTLIVKL ISIGEPQPDA TRVVYFELNG
1050
1051
QPREVVIKDE SIKSSVQERL KADRTNPSHI AASMPGTVIK VLAEAGTKVN
1100
1101
KGDHLMINEA MKMETTVQAP FSGTIKQVHV KNGEPIQTGD LLLEIEKA  
1148
 

Show the unformatted sequence.

Checksums:
CRC64:98D14DD56F361620
MD5:f950dcec6a661967245b71e573e17135

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;